product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
RWJ 67657
catalog :
2999/10
quantity :
10 mg
price :
217 USD
more info or order :
Tocris Bioscience product webpage
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
2999
SKU :
2999/10
product name :
RWJ 67657
description :
Potent, selective p38 and p38 inhibitor
target :
p38 Inhibitors
unit size :
10 mg
category :
Small Molecules
purity :
98%
storage :
Store at RT
observed molecular weight :
425.5
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
RWJ 67657 is a selective p38 and p38 inhibitor (IC50 values are 1 and 11 u M respectively) that displays no activity at p38 , p38 and a range of other kinases. Potently inhibits TNF- and IL-1 release (IC50 values are 3 and 11 nM respectively) and suppresses HIV-1 replication in T cells in vitro . Displays cardioprotective and anti-inflammatory activity in vivo . Orally active.
product keywords :
Potent selective p38 p38alpha p38 p38beta inhibitors inhibits MAPK Signaling Signalling Mitogen-Activated Protein Kinases RWJ67657 p38 2999,
extended description :
Potent, selective p38 and p38 inhibitor
chemical name text :
4-[4-(4-Fluorophenyl)-1-(3-phenylpropyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-3-butyn-1-ol
formula :
C27H24FN3O
formula text :
C27H24FN3O
cas num :
215303-72-3
USD :
241
USD 2025 :
217 USD
product details :
Potent, selective p38 and p38 inhibitor
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK