NS 1738 | Tocris Bioscience 2995/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NS 1738

catalog :

2995/10

quantity :

10 mg (also 50 mg)

price :

209 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Bali Z, Nagy L, Budai D, Hernadi I. Facilitation and inhibition of firing activity and N-methyl-D-aspartate-evoked responses of CA1 hippocampal pyramidal cells by alpha7 nicotinic acetylcholine receptor selective compounds in vivo. Sci Rep. 2019;9:9324 pubmed publisher
Chatzidaki A, D Oyley J, Gill Thind J, Sheppard T, Millar N. The influence of allosteric modulators and transmembrane mutations on desensitisation and activation of Î±7 nicotinic acetylcholine receptors. Neuropharmacology. 2015;97:75-85 pubmed publisher
Chatzidaki A, Fouillet A, Li J, Dage J, Millar N, Sher E, et al. Pharmacological Characterisation of Nicotinic Acetylcholine Receptors Expressed in Human iPSC-Derived Neurons. PLoS ONE. 2015;10:e0125116 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2995

SKU :

2995/10

product name :

NS 1738

description :

Positive allosteric modulator of 7 nAChRs; active in vivo

target :

Nicotinic (a7) Receptor Modulators

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at RT

observed molecular weight :

365.13

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

NS 1738 is a selective positive allosteric modulator of 7 nicotinic acetylcholine receptors. Exhibits no substantial activity for 4 2, 3 3 and 1-containing receptors. Displays cognitive-enhancing properties in vivo .

product keywords :

Positive allosteric modulators 7 alpha7 a7 nAChR active vivo Nicotinic Receptors Acetylcholine NS1738 PAM Nicotinic (a7) Receptors 2995,

extended description :

Positive allosteric modulator of 7 nAChRs; active in vivo

chemical name text :

N-(5-Chloro-2-hydroxyphenyl)-N -[2-chloro-5-(trifluoromethyl)phenyl]urea

formula :

C14H9Cl2F3N2O2

formula text :

C14H9Cl2F3N2O2

cas num :

501684-93-1

USD :

200

USD 2025 :

209 USD

product details :

Positive allosteric modulator of 7 nAChRs; active in vivo

more info or order :

Tocris Bioscience product webpage