product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
BIBR 1532
catalog :
2981
quantity :
10 mg (also 50 mg)
price :
216 USD
more info or order :
citations: 2
Reference
Beyer A, Freed J, Durand M, Riedel M, Ait Aissa K, Green P, et al. Critical Role for Telomerase in the Mechanism of Flow-Mediated Dilation in the Human Microcirculation. Circ Res. 2016;118:856-66 pubmed publisher
Farnung B, Brun C, Arora R, Lorenzi L, Azzalin C. Telomerase efficiently elongates highly transcribing telomeres in human cancer cells. PLoS ONE. 2012;7:e35714 pubmed publisher
product information
brand :
Tocris
master code :
2981
SKU :
2981/10
product name :
BIBR 1532
description :
Selective telomerase inhibitor
target :
Telomerase Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
331.36
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Selective telomerase inhibitor (IC50 values are 93, 100000 and 100000 nM for human telomerase, human RNA polymerase I and human RNA polymerase II + III respectively). Causes telomere shortening in exponentially growing NCI-H460 lung carcinoma cells and eventual growth arrest.
catalog number base :
2981
product keywords :
Selective telomerase inhibitors inhibits BIBR1532 Telomerase DNA, RNA and Protein Synthesis 2981,
extended description :
Selective telomerase inhibitor
chemical name text :
2-[[(2E)-3-(2-Naphthalenyl)-1-oxo-2-butenyl1-yl]amino]benzoic acid
formula :
C 21 H 17 NO 3
formula text :
C21H17NO3
cas num :
321674-73-1
2020 USD :
207
2021 USD :
216 USD
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK