PYR 41 | Tocris Bioscience 2978 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PYR 41

catalog :

2978

quantity :

10 mg

price :

229 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

2978

SKU :

2978/10

product name :

PYR 41

description :

Ubiquitin-activating enzyme (E1) inhibitor

target :

Ubiquitin-activating Enzyme (E1) Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

371.3

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Cell-permeable, irreversible ubiquitin-activating enzyme (E1) inhibitor (IC50 10 M). Blocks ubiquitination and prevents ubiquitin-mediated proteasomal degradation. Inhibits NF- B activation, blocks degradation of p53, increases p21 levels and induces apoptosis in vitro . Also causes an increase in sumoylation of proteins.

catalog number base :

2978

product keywords :

PYR41 ubiquitin-activating enzyme E1 inhibitors inhibits ubiquitylation post-translational modifications proteasomal proteasome sumoylation sumo ubiquitin Ubiquitin-activating Enzyme E1 Post-translational Modifications 2978,

extended description :

Ubiquitin-activating enzyme (E1) inhibitor

chemical name text :

4-[4-[(5-Nitro-2-furanyl)methylene]-3,5-dioxo-1-pyrazolidinyl]benzoic acid ethyl ester

formula :

C 17 H 13 N 3 O 7

formula text :

C17H13N3O7

cas num :

418805-02-4

2020 USD :

222

2021 USD :

229 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage