PYR 41 | Tocris Bioscience 2978/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PYR 41

catalog :

2978/10

quantity :

10 mg

price :

279 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 2978 - PYR 41 C17H13N3O7 CAS No. 418805-02-4

product information

brand :

Tocris

MasterCode :

2978

SKU :

2978/10

product name :

PYR 41

target :

Ubiquitin-activating Enzyme (E1) Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

371.3

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PYR 41 is a cell-permeable, irreversible ubiquitin-activating enzyme (E1) inhibitor (IC50 10 M). Blocks ubiquitination and prevents ubiquitin-mediated proteasomal degradation. Inhibits NF- B activation, blocks degradation of p53, increases p21 levels and induces apoptosis in vitro . Also causes an increase in sumoylation of proteins.

extended description :

Ubiquitin-activating enzyme (E1) inhibitor

chemical name text :

4-[4-[(5-Nitro-2-furanyl)methylene]-3,5-dioxo-1-pyrazolidinyl]benzoic acid ethyl ester

formula :

C 17 H 13 N 3 O 7

formula text :

C17H13N3O7

cas num :

418805-02-4

USD :

279 USD

product details :

Ubiquitin-activating enzyme (E1) inhibitor

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage