SR 12813 | Tocris Bioscience 2969/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SR 12813

catalog :

2969/10

quantity :

10 mg (also 50 mg)

price :

132 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Delfosse V, Dendelé B, Huet T, Grimaldi M, Boulahtouf A, Gerbal Chaloin S, et al. Synergistic activation of human pregnane X receptor by binary cocktails of pharmaceutical and environmental compounds. Nat Commun. 2015;6:8089 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2969

SKU :

2969/10

product name :

SR 12813

description :

Pregnane X receptor agonist

target :

Pregnane X Receptor Agonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

99%

storage :

Store at +4°C

observed molecular weight :

504.53

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SR 12813 is a pregnane X receptor (PXR) agonist (EC50 values are 200 and 700 nM for human and rabbit PXR respectively). Activates the farnesoid X receptor (FXR) at u M concentrations. Displays hypocholesterolemic activity via enhanced degradation of HMG-CoA reductase.

product keywords :

Pregnane X receptor PXR agonists Nuclear Receptors SR12813 HMG-CoA Reductase Pregnane X Receptor 2969,

extended description :

Pregnane X receptor agonist

chemical name text :

[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethenylidene]bis-phosphonic acid tetraethyl ester

formula :

C24H42O7P2

formula text :

C24H42O7P2

cas num :

126411-39-0

USD :

130

USD 2025 :

132 USD

product details :

Pregnane X receptor agonist

more info or order :

Tocris Bioscience product webpage