product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Spironolactone
catalog :
2968
quantity :
50 mg
price :
66 USD
more info or order :
citations: 3
Reference
Pinheiro B, Lemos C, Neutzling Kaufmann F, Marques J, da Silva Santos C, Carvalho E, et al. Hierarchical glucocorticoid-endocannabinoid interplay regulates the activation of the nucleus accumbens by insulin. Brain Res Bull. 2016;124:222-30 pubmed publisher
Liu Z, Song C, Wang M, He Y, Xu X, Pan H, et al. Chronic stress impairs GABAergic control of amygdala through suppressing the tonic GABAA receptor currents. Mol Brain. 2014;7:32 pubmed publisher
Thai C, Zhang Y, Howland J. Effects of acute restraint stress on set-shifting and reversal learning in male rats. Cogn Affect Behav Neurosci. 2013;13:164-73 pubmed publisher
product information
brand :
Tocris
master code :
2968
SKU :
2968/50
product name :
Spironolactone
description :
Mineralocorticoid receptor antagonist
target :
Mineralocorticoid Receptor Antagonists
category :
Small Molecules
unit size :
50 mg
purity :
98%
observed molecular weight :
416.57
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Competitive mineralocorticoid (aldosterone) receptor antagonist that exhibits antihypertensive activity in vivo . Also displays antiandrogen activity and inhibits steroid hormone biosynthesis.
catalog number base :
2968
product keywords :
Anti-Androgen AntiAndrogen inhibits inhibitors steroid hormone biosynthesis MR antagonists Mineralocorticoid receptor Dihydrotestosterone Receptors Androgen Aldosterone SC9420 SC 9420 Aldactone Mineralocorticoid Receptor Androgen Receptor 2968,
extended description :
Mineralocorticoid receptor antagonist
chemical name text :
(7 ,17 )-7-(Acetylthio)-17-hydroxy-3-oxopregn-4-ene-21-carboxylic acid -lactone
formula :
C 24 H 32 O 4 S
formula text :
C24H32O4S
cas num :
52-01-7
2020 USD :
64
2021 USD :
66 USD
alt names :
SC 9420, Aldactone
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK