CGP 3466B maleate | Tocris Bioscience 2966/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CGP 3466B maleate

catalog :

2966/10

quantity :

10 mg (also 50 mg)

price :

174 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Xu R, Serritella A, Sen T, Farook J, Sedlak T, BARABAN J, et al. Behavioral effects of cocaine mediated by nitric oxide-GAPDH transcriptional signaling. Neuron. 2013;78:623-30 pubmed publisher

product information

brand :

Tocris

master code :

2966

SKU :

2966/10

product name :

CGP 3466B maleate

description :

GAPDH inhibitor; neuroprotective

target :

Dehydrogenase Inhibitors

category :

Small Molecules

unit sizes :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

391.42

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CGP 3466B maleate is an orally active glyceraldehyde-3-phosphate dehydrogenase (GAPDH) inhibitor. Exhibits antiapoptotic activity via inhibition of GAPDH nuclear translocation and mitochondrial complex 1-dependent H2O2 release. CGP 3466B inhibits colon cancer proliferation in vitro and displays neuroprotective activity in vivo .

extended description :

GAPDH inhibitor; neuroprotective

chemical name text :

N-(Dibenz[b,f]oxepin-10-ylmethyl)-N-Methyl-N-(2-propynyl)amine maleate

formula :

C 19 H 17 NO.C 4 H 4 O 4

formula text :

C19H17NO.C4H4O4

cas num :

200189-97-5

USD :

174 USD

product details :

GAPDH inhibitor; neuroprotective

alt names :

TCH 346 maleate

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage