Org 27569 | Tocris Bioscience 2957 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Org 27569

catalog :

2957

quantity :

10 mg (also 50 mg)

price :

191 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Cawston E, Redmond W, Breen C, Grimsey N, Connor M, Glass M. Real-time characterization of cannabinoid receptor 1 (CB1 ) allosteric modulators reveals novel mechanism of action. Br J Pharmacol. 2013;170:893-907 pubmed publisher
Baillie G, Horswill J, Anavi Goffer S, Reggio P, Bolognini D, Abood M, et al. CB(1) receptor allosteric modulators display both agonist and signaling pathway specificity. Mol Pharmacol. 2013;83:322-38 pubmed publisher

product information

brand :

Tocris

master code :

2957

SKU :

2957/10

product name :

Org 27569

description :

Potent allosteric modulator of CB1 receptors

target :

Cannabinoid R1/CB1 Modulators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

409.95

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent CB1 receptor allosteric modulator (pEC50 = 8.24). Significantly increases binding of the CB1 agonist [3H]CP 55.940 (pKb = 5.67) and decreases binding of the CB1 inverse agonist [3H]SR 141716A (pKb = 5.95). Inhibits CB1 receptor antagonist efficacy in vitro (pKb = 7.57).

catalog number base :

2957

product keywords :

Potent allosteric CB1 modulators cannabinoids Receptors Org27569 cb1r CB1 Receptors 2957,

extended description :

Potent allosteric modulator of CB1 receptors

chemical name text :

5-Chloro-3-ethyl-N-[2-[4-(1-piperidinyl)phenyl]ethyl-1H-indole-2-carboxamide

formula :

C 24 H 28 ClN 3 O

formula text :

C24H28ClN3O

cas num :

868273-06-7

2020 USD :

185

2021 USD :

191 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage