CyPPA | Tocris Bioscience 2953/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CyPPA

catalog :

2953/5

quantity :

5 mg (also 25 mg)

price :

131 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Abdulkareem Z, Gee J, Cox C, Wann K. Knockdown of the small conductance Ca(2+) -activated K(+) channels is potently cytotoxic in breast cancer cell lines. Br J Pharmacol. 2016;173:177-90 pubmed publisher
Benton M, Lewis A, Bant J, Raman I. Iberiotoxin-sensitive and -insensitive BK currents in Purkinje neuron somata. J Neurophysiol. 2013;109:2528-41 pubmed publisher

image

image 1 :

Cat.No. 2953 - CyPPA C16H23N5 CAS No. 73029-73-9

product information

brand :

Tocris

catalog number base :

2953

SKU :

2953/5

product name :

CyPPA

units size :

5 mg (also 25 mg)

description :

KCa2.2 and KCa2.3 (SK) channel activator

target :

Ca2+-Activated Potassium Channel Activators

category :

Small Molecules

purity :

99%

observed molecular weight :

285.39

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

review stars :

details of functionality :

CyPPA is an activator of small conductance Ca2+-activated K+ channels that displays selectivity for KCa2.2 (SK2) and KCa2.3 (SK3) channels (EC50 values are 5.6 and 14 u M for KCa2.3 and KCa2.2 respectively). Displays no activity at KCa2.1 (SK1) and KCa3.1 (IK) channels.

top caption :

KCa2.2 and KCa2.3 (SK) channel activator

extended description :

KCa2.2 and KCa2.3 (SK) channel activator

chemical name text :

N-Cyclohexyl-N-[2-(3,5-dimethyl-pyrazol-1-yl)-6-methyl-4-pyrimidinamine

formula :

C16H23N5

formula text :

C16H23N5

cas num :

73029-73-9

USD :

131 USD

product details :

KCa2.2 and KCa2.3 (SK) channel activator

storage :

Store at +4Â°C

more info or order :

Tocris Bioscience product webpage