Acetyl-calpastatin 184-210 (human) | Tocris Bioscience 2950/1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Acetyl-calpastatin 184-210 (human)

catalog :

2950/1

quantity :

1 mg

price :

424 USD

citations: 3

Reference
Alvarez Arce A, Lee Rivera I, Lopez E, Hernandez Cruz A, López Colomé A. Thrombin-Induced Calpain Activation Promotes Protease-Activated Receptor 1 Internalization. Int J Cell Biol. 2017;2017:1908310 pubmed publisher
Gerónimo Olvera C, Montiel T, Rincon Heredia R, Castro Obregon S, Massieu L. Autophagy fails to prevent glucose deprivation/glucose reintroduction-induced neuronal death due to calpain-mediated lysosomal dysfunction in cortical neurons. Cell Death Dis. 2017;8:e2911 pubmed publisher
Davis B, Stucke E, Khorki M, LITOSH V, Rymer J, Rochman M, et al. Eosinophilic esophagitis-linked calpain 14 is an IL-13-induced protease that mediates esophageal epithelial barrier impairment. JCI Insight. 2016;1:e86355 pubmed

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

2950

SKU :

2950/1

product name :

Acetyl-calpastatin 184-210 (human)

Description :

Selective calpain inhibitor

target :

Calpain Inhibitors

category :

Peptides

unit size :

1 mg

purity :

95%

species :

Human

observed molecular weight :

3177.65

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Acetyl-Calpastatin (184-210) (human) is a selective calpain inhibitor. Strongly inhibits calpain I (Ki = 0.2 nM) and II but does not inhibit papain, trypsin and cathepsin L (Ki = 6 u M). Increases secretion of amyoid -protein (A ) 42, A 40 and A 42 ratio.

extended description :

Selective calpain inhibitor

formula :

C 142 H 230 N 36 O 44 S

formula text :

C142H230N36O44S

cas num :

123714-50-1

USD :

424 USD

product details :

Selective calpain inhibitor

storage :

Store at -20°C