SNX 482 | Tocris Bioscience 2945/10U product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SNX 482

catalog :

2945/10U

quantity :

10 ug

price :

243 USD

citations: 7

Reference
Smith M, Katsouri L, Virtue S, Choudhury A, Vidal Puig A, Ashford M, et al. Calcium Channel CaV2.3 Subunits Regulate Hepatic Glucose Production by Modulating Leptin-Induced Excitation of Arcuate Pro-opiomelanocortin Neurons. Cell Rep. 2018;25:278-287.e4 pubmed publisher
Hashiguchi H, Sheng Z, Routh V, Gerzanich V, Simard J, Bryan J. Direct versus indirect actions of ghrelin on hypothalamic NPY neurons. PLoS ONE. 2017;12:e0184261 pubmed publisher
Pan B, Guo Y, Kwok W, Hogan Q, Wu H. Sigma-1 receptor antagonism restores injury-induced decrease of voltage-gated Ca2+ current in sensory neurons. J Pharmacol Exp Ther. 2014;350:290-300 pubmed publisher
Brennan S, Finney B, Lazarou M, Rosser A, Scherf C, Adriaensen D, et al. Fetal calcium regulates branching morphogenesis in the developing human and mouse lung: involvement of voltage-gated calcium channels. PLoS ONE. 2013;8:e80294 pubmed publisher
Goswami S, Bucurenciu I, Jonas P. Miniature IPSCs in hippocampal granule cells are triggered by voltage-gated Ca2+ channels via microdomain coupling. J Neurosci. 2012;32:14294-304 pubmed publisher
Higley M, Sabatini B. Competitive regulation of synaptic Ca2+ influx by D2 dopamine and A2A adenosine receptors. Nat Neurosci. 2010;13:958-66 pubmed publisher
Grubb M, Burrone J. Activity-dependent relocation of the axon initial segment fine-tunes neuronal excitability. Nature. 2010;465:1070-4 pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

2945

SKU :

2945/10U

product name :

SNX 482

Description :

Potent and selective CaV2.3 blocker

target :

Cav2.x Channel Blockers

category :

Peptides

unit size :

10 ug

observed molecular weight :

4495.01

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

SNX 482 is a potent and selective, voltage-dependent R-type CaV2.3 calcium channel blocker (IC50 = 30 nM). Antinociceptive; inhibits nociceptive C-fibre and A -fibre-evoked neuronal responses.

extended description :

Potent and selective CaV2.3 blocker

formula :

C 192 H 274 N 52 O 60 S 7

formula text :

C192H274N52O60S7

cas num :

203460-30-4

USD :

243 USD

product details :

Potent and selective CaV2.3 blocker

storage :

Desiccate at -20°C