Venlafaxine hydrochloride | Tocris Bioscience 2917 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Venlafaxine hydrochloride

catalog :

2917

quantity :

10 mg (also 50 mg)

price :

127 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Stuart S, Butler P, MunafÃ² M, Nutt D, Robinson E. Distinct Neuropsychological Mechanisms May Explain Delayed- Versus Rapid-Onset Antidepressant Efficacy. Neuropsychopharmacology. 2015;40:2165-74 pubmed publisher
Yuen E, Qin L, Wei J, Liu W, Liu A, Yan Z. Synergistic regulation of glutamatergic transmission by serotonin and norepinephrine reuptake inhibitors in prefrontal cortical neurons. J Biol Chem. 2014;289:25177-85 pubmed publisher
Stuart S, Butler P, MunafÃ² M, Nutt D, Robinson E. A translational rodent assay of affective biases in depression and antidepressant therapy. Neuropsychopharmacology. 2013;38:1625-35 pubmed publisher

product information

brand :

Tocris

master code :

2917

SKU :

2917/10

product name :

Venlafaxine hydrochloride

description :

5-HT and NA reuptake inhibitor (SNRI)

target :

5-HT Transporter Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

313.86

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Dual serotonin/noradrenalin re-uptake inhibitor that displays ~ 30-fold higher affinity for SERT than NET (Ki values are 82 and 2480 nM respectively). Antidepressant; increases swimming and climbing behavior in the forced-swim test in rats.

catalog number base :

2917

product keywords :

Dual serotonin/noradrenaline reuptake inhibitors inhibits NET Adrenergic Transporters Monoamine Neurotransmitter SERT 5-HT 5-Hydroxytryptamine Wy45030 Wy 45030 5-HT Transporters Adrenergic Transporters 2917,

extended description :

5-HT and NA reuptake inhibitor (SNRI)

chemical name text :

1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride

formula :

C 17 H 27 NO 2 .HCl

formula text :

C17H27NO2.HCl

cas num :

99300-78-4

2020 USD :

124

2021 USD :

127 USD

alt names :

Wy 45030

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage