product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Venlafaxine hydrochloride
catalog :
2917/10
quantity :
10 mg (also 50 mg)
price :
143 USD
more info or order :
citations: 3
Reference
Stuart S, Butler P, Munafò M, Nutt D, Robinson E. Distinct Neuropsychological Mechanisms May Explain Delayed- Versus Rapid-Onset Antidepressant Efficacy. Neuropsychopharmacology. 2015;40:2165-74 pubmed publisher
Yuen E, Qin L, Wei J, Liu W, Liu A, Yan Z. Synergistic regulation of glutamatergic transmission by serotonin and norepinephrine reuptake inhibitors in prefrontal cortical neurons. J Biol Chem. 2014;289:25177-85 pubmed publisher
Stuart S, Butler P, Munafò M, Nutt D, Robinson E. A translational rodent assay of affective biases in depression and antidepressant therapy. Neuropsychopharmacology. 2013;38:1625-35 pubmed publisher
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
2917
SKU :
2917/10
product name :
Venlafaxine hydrochloride
description :
5-HT and NA reuptake inhibitor (SNRI)
target :
5-HT Transporter Inhibitors
unit size :
10 mg (also 50 mg)
category :
Small Molecules
purity :
99%
storage :
Store at RT
observed molecular weight :
313.86
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Venlafaxine hydrochloride is a dual serotonin/noradrenalin re-uptake inhibitor that displays ~ 30-fold higher affinity for SERT than NET (Ki values are 82 and 2480 nM respectively). Antidepressant; increases swimming and climbing behavior in the forced-swim test in rats.
product keywords :
Dual serotonin/noradrenaline reuptake inhibitors inhibits NET Adrenergic Transporters Monoamine Neurotransmitter SERT 5-HT 5-Hydroxytryptamine Wy45030 Wy 45030 5-HT Transporters Adrenergic Transporters 2917,
extended description :
5-HT and NA reuptake inhibitor (SNRI)
chemical name text :
1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride
formula :
C17H27NO2.HCl
formula text :
C17H27NO2.HCl
cas num :
99300-78-4
USD :
158
USD 2025 :
143 USD
product details :
5-HT and NA reuptake inhibitor (SNRI)
alt names :
Wy 45030
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK