product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
TRO 19622
catalog :
2906
quantity :
10 mg (also 50 mg)
price :
129 USD
more info or order :
citations: 1
Reference
Skals M, Bjaelde R, Reinholdt J, Poulsen K, Vad B, Otzen D, et al. Bacterial RTX toxins allow acute ATP release from human erythrocytes directly through the toxin pore. J Biol Chem. 2014;289:19098-109 pubmed publisher
product information
brand :
Tocris
master code :
2906
SKU :
2906/10
product name :
TRO 19622
description :
Binds voltage-dependent anion channel (VDAC)
target :
Ion Channel Modulators
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
399.65
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Neuroprotective and neuroregenerative compound. Rescues motor neurons from axotomy-induced cell death and promotes nerve regeneration following sciatic nerve crush in vivo . Binds directly to two components of the mitochondrial permeability pore, the voltage-dependent anion channel (VDAC) and translocator protein; thought to inhibit MPTP opening.
catalog number base :
2906
product keywords :
Neuroprotective neuroregenerative Binds voltage-dependent anion VDAC Channels modulators Other TRO19622 mitochondrial pore MPTP olesoxime spinal muscular atrophy SMA Olesoxime Other Channel Modulators Miscellaneous Compounds MPTP 2906,
extended description :
Binds voltage-dependent anion channel (VDAC)
chemical name text :
Cholest-4-en-3-one oxime
formula :
C 27 H 45 NO
formula text :
C27H45NO
cas num :
22033-87-0
2020 USD :
124
2021 USD :
129 USD
alt names :
Olesoxime
storage :
Desiccate at +4°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK