TB 21007 | Tocris Bioscience 2905/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TB 21007

catalog :

2905/10

quantity :

10 mg (also 50 mg)

price :

225 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
De la Luz Cuellar Y, Rodríguez Palma E, Franco Enzástiga Ú, Salinas Abarca A, Delgado Lezama R, Granados Soto V. Blockade of spinal α5-GABAA receptors differentially reduces reserpine-induced fibromyalgia-type pain in female rats. Eur J Pharmacol. 2019;:172443 pubmed publisher
Koh M, Rosenzweig Lipson S, Gallagher M. Selective GABA(A) ?5 positive allosteric modulators improve cognitive function in aged rats with memory impairment. Neuropharmacology. 2013;64:145-52 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2905

SKU :

2905/10

product name :

TB 21007

description :

5-selective GABAA inverse agonist

target :

GABA-A Receptor Inverse Agonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

99%

storage :

Store at +4°C

observed molecular weight :

339.5

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TB 21007 is a GABAA receptor inverse agonist selective for the 5-subtype (Ki values are 1.6, 16, 20 and 20 nM for 5, 2, 1 and 3 subtypes respectively). Brain penetrant; enhances cognitive performance in rats in the delayed matching-to-place morris water maze test following i.p. administration.

product keywords :

5 alpha5-selective GABAA inverse agonists Receptors TB21007 GABAA Receptors 2905,

extended description :

5-selective GABAA inverse agonist

chemical name text :

6,7-Dihydro-3-[(2-hydroxyethyl)thio]-6,6-dimethyl-1-(2-thiazolyl)-benzo[c]thiophen-4(5H)-one

formula :

C15H17NO2S3

formula text :

C15H17NO2S3

cas num :

207306-50-1

USD :

222

USD 2025 :

225 USD

product details :

5-selective GABAA inverse agonist

more info or order :

Tocris Bioscience product webpage