product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Granisetron hydrochloride
catalog :
2903/10
quantity :
10 mg (also 50 mg)
price :
96 USD
more info or order :
citations: 5
Reference
Luo F, Tran A, Xin L, Sanapala C, Lang B, Silver J, et al. Modulation of proteoglycan receptor PTPσ enhances MMP-2 activity to promote recovery from multiple sclerosis. Nat Commun. 2018;9:4126 pubmed publisher
Gerhold K, Drdla Schutting R, Honsek S, Forsthuber L, Sandkühler J. Pronociceptive and Antinociceptive Effects of Buprenorphine in the Spinal Cord Dorsal Horn Cover a Dose Range of Four Orders of Magnitude. J Neurosci. 2015;35:9580-94 pubmed publisher
Otvos R, Iyer J, van Elk R, Ulens C, Niessen W, Somsen G, et al. Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms. Toxins (Basel). 2015;7:2336-53 pubmed publisher
Murray K, Stephens M, Rank M, D Amico J, Gorassini M, Bennett D. Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors. J Neurophysiol. 2011;106:925-43 pubmed publisher
Carlson S, Fieber L. Unique ionotropic receptors for D-aspartate are a target for serotonin-induced synaptic plasticity in Aplysia californica. Comp Biochem Physiol C Toxicol Pharmacol. 2012;155:151-9 pubmed publisher
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
2903
SKU :
2903/10
product name :
Granisetron hydrochloride
description :
5-HT3 antagonist
target :
5-HT3 Receptor Antagonists
unit size :
10 mg (also 50 mg)
category :
Small Molecules
purity :
99%
storage :
Desiccate at +4°C
observed molecular weight :
348.87
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Granisetron hydrochloride is a 5-HT3 receptor antagonist that possesses potent antiemetic activity.
product keywords :
5-HT3 antagonists Serotonin Receptors BRL43694 BRL 43694 5-HT3 Receptors 2903,
extended description :
5-HT3 antagonist
chemical name text :
1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide hydrochloride
formula :
C18H24N4O.HCl
formula text :
C18H24N4O.HCl
cas num :
107007-99-8
USD :
95
USD 2025 :
96 USD
product details :
5-HT3 antagonist
alt names :
BRL 43694
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK