UK 370106 | Tocris Bioscience 2900/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

UK 370106

catalog :

2900/10

quantity :

10 mg

price :

314 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Ã…gren M, Schnabel R, Christensen L, Mirastschijski U. Tumor necrosis factor-Î±-accelerated degradation of type I collagen in human skin is associated with elevated matrix metalloproteinase (MMP)-1 and MMP-3 ex vivo. Eur J Cell Biol. 2015;94:12-21 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2900

SKU :

2900/10

product name :

UK 370106

description :

Highly selective MMP-3 and MMP-12 inhibitor

target :

Synthetic Metalloprotease Inhibitors

unit size :

10 mg

category :

Small Molecules

purity :

95%

storage :

Store at -20°C

observed molecular weight :

572.73

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

UK 370106 is a highly selective MMP-3 and MMP-12 inhibitor (IC50 values are 0.023, 0.042, 1.75, 2.3, 5.8, 30.4, 34.2 and 66.9 M at MMP 3, 12, 8, 13, 7, 9, 2 and 14 respectively.) Inhibits fibronectin cleavage (IC50 = 320 nM) and has little effect on keratinocyte migration in vitro . Substantially inhibits MMP-3 in an ex vivo model of chronic dermal ulcers.

product keywords :

selective MMP-3 MMP-12 inhibitors inhibits Matrixins Matrix Metalloproteinase MMP Metalloprotease Proteinases Proteases UK370106 Matrix Metalloprotease 2900,

extended description :

Highly selective MMP-3 and MMP-12 inhibitor

chemical name text :

( R)- -[[[(1S)-1-[[[(1S)-2-Methoxy-1-phenylethyl]amino]carbonyl]-2,2-dimethylpropyl]amino]carbonyl]-2-methyl-[1,1 -biphenyl]-4-hexanoic acid

formula :

C35H44N2O5

formula text :

C35H44N2O5

cas num :

230961-21-4

USD :

310

USD 2025 :

314 USD

product details :

Highly selective MMP-3 and MMP-12 inhibitor

more info or order :

Tocris Bioscience product webpage