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company name :
Tocris Bioscience
product type :
chemical
product name :
Dynasore
catalog :
2897
quantity :
10 mg (also 50 mg)
price :
148 USD
more info or order :
citations: 29
Reference
Sole L, Wagnon J, Akin E, Meisler M, Tamkun M. The MAP1B Binding Domain of Nav1.6 Is Required for Stable Expression at the Axon Initial Segment. J Neurosci. 2019;39:4238-4251 pubmed publisher
Lorenz Guertin J, Wilcox M, Zhang M, Larsen M, Pilli J, Schmidt B, et al. A versatile optical tool for studying synaptic GABAA receptor trafficking. J Cell Sci. 2017;130:3933-3945 pubmed publisher
Pitt J, Wilcox K, Tortelli V, Diniz L, Oliveira M, Dobbins C, et al. Neuroprotective astrocyte-derived insulin/insulin-like growth factor 1 stimulates endocytic processing and extracellular release of neuron-bound A? oligomers. Mol Biol Cell. 2017;28:2623-2636 pubmed publisher
Blume L, Leone Kabler S, Luessen D, Marrs G, Lyons E, Bass C, et al. Cannabinoid receptor interacting protein suppresses agonist-driven CB1 receptor internalization and regulates receptor replenishment in an agonist-biased manner. J Neurochem. 2016;139:396-407 pubmed publisher
Hallstrom K, McCormick B. The type three secreted effector SipC regulates the trafficking of PERP during Salmonella infection. Gut Microbes. 2016;7:136-45 pubmed publisher
von Hoven G, Neukirch C, Meyenburg M, Füser S, Petrivna M, Rivas A, et al. eIF2α Confers Cellular Tolerance to S. aureus α-Toxin. Front Immunol. 2015;6:383 pubmed publisher
Petermann P, Rahn E, Thier K, Hsu M, Rixon F, Kopp S, et al. Role of Nectin-1 and Herpesvirus Entry Mediator as Cellular Receptors for Herpes Simplex Virus 1 on Primary Murine Dermal Fibroblasts. J Virol. 2015;89:9407-16 pubmed publisher
Falgairolle M, O Donovan M. Pharmacological Investigation of Fluoro-Gold Entry into Spinal Neurons. PLoS ONE. 2015;10:e0131430 pubmed publisher
Nimlamool W, Andrews R, Falk M. Connexin43 phosphorylation by PKC and MAPK signals VEGF-mediated gap junction internalization. Mol Biol Cell. 2015;26:2755-68 pubmed publisher
Khatua A, Cheatham A, Kruzel E, Singhal P, Skorecki K, Popik W. Exon 4-encoded sequence is a major determinant of cytotoxicity of apolipoprotein L1. Am J Physiol Cell Physiol. 2015;309:C22-37 pubmed publisher
Niederst E, Reyna S, Goldstein L. Axonal amyloid precursor protein and its fragments undergo somatodendritic endocytosis and processing. Mol Biol Cell. 2015;26:205-17 pubmed publisher
Lee W, Leddy H, Chen Y, Lee S, Zelenski N, McNulty A, et al. Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage. Proc Natl Acad Sci U S A. 2014;111:E5114-22 pubmed publisher
Ledonne A, Nobili A, Latagliata E, Cavallucci V, Guatteo E, Puglisi Allegra S, et al. Neuregulin 1 signalling modulates mGluR1 function in mesencephalic dopaminergic neurons. Mol Psychiatry. 2015;20:959-73 pubmed publisher
Pribiag H, Stellwagen D. TNF-? downregulates inhibitory neurotransmission through protein phosphatase 1-dependent trafficking of GABA(A) receptors. J Neurosci. 2013;33:15879-93 pubmed publisher
Marcello E, Saraceno C, Musardo S, Vara H, de la Fuente A, Pelucchi S, et al. Endocytosis of synaptic ADAM10 in neuronal plasticity and Alzheimer's disease. J Clin Invest. 2013;123:2523-38 pubmed publisher
Chandrasekaran P, Buckley M, Moore V, Wang L, Kehrl J, Venkatesan S. HIV-1 Nef impairs heterotrimeric G-protein signaling by targeting G?(i2) for degradation through ubiquitination. J Biol Chem. 2012;287:41481-98 pubmed publisher
Hollidge B, Nedelsky N, Salzano M, Fraser J, Gonzalez Scarano F, Soldan S. Orthobunyavirus entry into neurons and other mammalian cells occurs via clathrin-mediated endocytosis and requires trafficking into early endosomes. J Virol. 2012;86:7988-8001 pubmed publisher
Bassani S, Cingolani L, Valnegri P, Folci A, Zapata J, Gianfelice A, et al. The X-linked intellectual disability protein TSPAN7 regulates excitatory synapse development and AMPAR trafficking. Neuron. 2012;73:1143-58 pubmed publisher
Lee J, Ho W, Lee S. Actin-dependent rapid recruitment of reluctant synaptic vesicles into a fast-releasing vesicle pool. Proc Natl Acad Sci U S A. 2012;109:E765-74 pubmed publisher
Rahn E, Petermann P, Hsu M, Rixon F, Knebel Mörsdorf D. Entry pathways of herpes simplex virus type 1 into human keratinocytes are dynamin- and cholesterol-dependent. PLoS ONE. 2011;6:e25464 pubmed publisher
Rodriguez J, Luria Pérez R, López Valdés H, Casero D, Daniels T, Patel S, et al. Lethal iron deprivation induced by non-neutralizing antibodies targeting transferrin receptor 1 in malignant B cells. Leuk Lymphoma. 2011;52:2169-78 pubmed publisher
Zemskov E, Mikhailenko I, Hsia R, Zaritskaya L, Belkin A. Unconventional secretion of tissue transglutaminase involves phospholipid-dependent delivery into recycling endosomes. PLoS ONE. 2011;6:e19414 pubmed publisher
Yang M, Reich D, Chen C. Measurement and analysis of traction force dynamics in response to vasoactive agonists. Integr Biol (Camb). 2011;3:663-74 pubmed publisher
Lussier M, Nasu Nishimura Y, Roche K. Activity-dependent ubiquitination of the AMPA receptor subunit GluA2. J Neurosci. 2011;31:3077-81 pubmed publisher
Lowther K, Nikolaev V, Mehlmann L. Endocytosis in the mouse oocyte and its contribution to cAMP signaling during meiotic arrest. Reproduction. 2011;141:737-47 pubmed publisher
Park S, Kim K, Lindsey J, Dai Y, Heo H, Nguyen D, et al. A selective inhibitor of drp1, mdivi-1, increases retinal ganglion cell survival in acute ischemic mouse retina. Invest Ophthalmol Vis Sci. 2011;52:2837-43 pubmed publisher
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Kolpak A, Jiang J, Guo D, Standley C, Bellve K, Fogarty K, et al. Negative guidance factor-induced macropinocytosis in the growth cone plays a critical role in repulsive axon turning. J Neurosci. 2009;29:10488-98 pubmed publisher
product information
brand :
Tocris
master code :
2897
SKU :
2897/10
product name :
Dynasore
description :
Non-competitive dynamin inhibitor
target :
Dynamin Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
99%
observed molecular weight :
322.32
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Non-competitive inhibitor of dynamin 1, dynamin 2 and mitochondrial dynamin (Drp1) GTPase activity. Does not inhibit other small GTPases. Blocks endocytic pathways dependent on dynamin and inhibits cell spreading and migration of BSC1 cells.
catalog number base :
2897
product keywords :
Non-competitive dynamin 1 2 mitochondrial Drp1 inhibitors inhibits Mitosis GTPases Mitosis Dynamin 2897,
extended description :
Non-competitive dynamin inhibitor
chemical name text :
3-Hydroxynaphthalene-2-carboxylic acid (3,4-dihydroxybenzylidene)hydrazide
formula :
C 18 H 14 N 2 O 4
formula text :
C18H14N2O4
cas num :
304448-55-3
2020 USD :
145
2021 USD :
148 USD
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK