Flupirtine maleate | Tocris Bioscience 2867 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Flupirtine maleate

catalog :

2867

quantity :

10 mg (also 50 mg)

price :

107 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Sedivy V, Joshi S, Ghaly Y, Mizera R, Žaloudíková M, Brennan S, et al. Role of Kv7 channels in responses of the pulmonary circulation to hypoxia. Am J Physiol Lung Cell Mol Physiol. 2015;308:L48-57 pubmed publisher
Lee B, Ryu P, Lee S. Serum starvation-induced voltage-gated potassium channel Kv7.5 expression and its regulation by Sp1 in canine osteosarcoma cells. Int J Mol Sci. 2014;15:977-93 pubmed publisher

product information

brand :

Tocris

master code :

2867

SKU :

2867/10

product name :

Flupirtine maleate

description :

KV7 channel activator; also GABAA modulator and indirect NMDA antagonist

target :

Non-selective/Other Potassium Channel Activators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

420.4

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Non-opioid analgesic with muscle relaxant properties. Activates KV7 potassium channels, indirectly antagonizes NMDA receptors and modulates GABAA receptors. Exhibits neuroprotective actions in a model of cerebral ischemia in mice and reduces apoptosis and necrosis induced by noxious stimuli.

catalog number base :

2867

product keywords :

K+ channel activators Indirect NMDA receptors antagonists Potassium Channels kv7 GABA GABAA Glutamate Receptors N-Methyl-D-Aspartate iGluR Ionotropic D9998 D 9998 Voltage-Gated Potassium Channels NMDA Receptors GABAA Receptors 2867,

extended description :

KV7 channel activator; also GABAA modulator and indirect NMDA antagonist

chemical name text :

N-[2-Amino-6-[[4-fluorophenyl)methyl]amino]-3-pyridinyl]carbamic acid ethyl ester maleate

formula :

C 15 H 17 FN 4 O 2 .C 4 H 4 O 4

formula text :

C15H17FN4O2.C4H4O4

cas num :

75507-68-5

2020 USD :

102

2021 USD :

107 USD

alt names :

D 9998

storage :

Desiccate at +4°C

more info or order :

Tocris Bioscience product webpage