Adapalene | Tocris Bioscience 2852/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Adapalene

catalog :

2852/10

quantity :

10 mg (also 50 mg)

price :

104 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Whelan J, Wang L, Chen J, Metts M, Nasser T, McGoldrick L, et al. Retinoids induce integrin-independent lymphocyte adhesion through RAR-Î± nuclear receptor activity. Biochem Biophys Res Commun. 2014;454:537-42 pubmed publisher
Huk D, Hammond H, Kegechika H, Lincoln J. Increased dietary intake of vitamin A promotes aortic valve calcification in vivo. Arterioscler Thromb Vasc Biol. 2013;33:285-93 pubmed publisher
Gupta K, Gulen F, Sun L, Aguilera R, Chakrabarti A, Kiselar J, et al. GSK3 is a regulator of RAR-mediated differentiation. Leukemia. 2012;26:1277-85 pubmed publisher
Dhandapani L, Yue P, Ramalingam S, Khuri F, Sun S. Retinoic acid enhances TRAIL-induced apoptosis in cancer cells by upregulating TRAIL receptor 1 expression. Cancer Res. 2011;71:5245-54 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2852

SKU :

2852/10

product name :

Adapalene

description :

RAR and RAR agonist

target :

Retinoic Acid Receptor Agonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

412.52

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Adapalene is a retinoic acid analog that is a RAR and RAR agonist (AC50 values are 2.2, 9.3, 22 and 1000 nM for RAR , RAR , RAR and RXR receptors respectively). Inhibits proliferation and induces apoptosis in colorectal cancer cell in vitro . Displays comedolytic activity.

product keywords :

RAR RARbeta RAR RARgamma agonists Retinoic Acid Receptors CD271 CD 271 Differin Retinoic Acid Receptors 2852,

extended description :

RAR and RAR agonist

chemical name text :

6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic acid

formula :

C28H28O3

formula text :

C28H28O3

cas num :

106685-40-9

USD :

115

USD 2025 :

104 USD

product details :

RAR and RAR agonist

alt names :

CD 271,Differin

more info or order :

Tocris Bioscience product webpage