product summary
Loading...
company name :
Tocris Bioscience
product type :
chemical
product name :
Curcumin
catalog :
2841
quantity :
50 mg
price :
73 USD
more info or order :
citations: 5
Reference
Boija A, Mahat D, Zare A, Holmqvist P, Philip P, Meyers D, et al. CBP Regulates Recruitment and Release of Promoter-Proximal RNA Polymerase II. Mol Cell. 2017;68:491-503.e5 pubmed publisher
Chang L, Cui W, Yang Y, Xu S, Zhou W, Fu H, et al. Protection against β-amyloid-induced synaptic and memory impairments via altering β-amyloid assembly by bis(heptyl)-cognitin. Sci Rep. 2015;5:10256 pubmed publisher
Efthymiou A, Steiner J, Pavan W, Wincovitch S, Larson D, Porter F, et al. Rescue of an in vitro neuron phenotype identified in Niemann-Pick disease, type C1 induced pluripotent stem cell-derived neurons by modulating the WNT pathway and calcium signaling. Stem Cells Transl Med. 2015;4:230-8 pubmed publisher
Chen M, Lee M, Chuang J, Li Y, Ning S, Chen J, et al. Curcumin inhibits HCV replication by induction of heme oxygenase-1 and suppression of AKT. Int J Mol Med. 2012;30:1021-8 pubmed publisher
Han Y, Lee S, Jeong H, Kim M, Yoon M, Kim W. Analgesic effects of intrathecal curcumin in the rat formalin test. Korean J Pain. 2012;25:1-6 pubmed publisher
product information
brand :
Tocris
master code :
2841
SKU :
2841/50
product name :
Curcumin
description :
Antitumor, anti-inflammatory and antioxidant
target :
Apoptosis Inducer Compounds
category :
Small Molecules
unit size :
50 mg
observed molecular weight :
368.38
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Antitumor, anti-inflammatory and antioxidant agent. Downregulates expression of reactive-oxygen-generating enzymes (cyclooxygenase, lipoxygenase, iNOS), TNF , IL-1, IL-6, PKC, EGFR, NF- B, I B kinase and more. Upregulates expression of PPAR , p53, Nrf2. Also displays antimicrobial, antidiabetic neuro- and cardioprotective properties in vivo .
catalog number base :
2841
product keywords :
Antitumor anti-inflammatory antioxidant Apoptosis Inducer nrf2 Diferuloylmethane Apoptosis Inducers Antioxidants Nrf2 2841,
extended description :
Antitumor, anti-inflammatory and antioxidant
chemical name text :
(1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
formula :
C 21 H 20 O 6
formula text :
C21H20O6
cas num :
458-37-7
2020 USD :
71
2021 USD :
73 USD
alt names :
Diferuloylmethane
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK