BDNF (human) | Tocris Bioscience 2837/10U product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BDNF (human)

catalog :

2837/10U

quantity :

10 ug

price :

426 USD

more info or order :

Tocris Bioscience product webpage

citations: 6

Reference
Hashimotodani Y, Nasrallah K, Jensen K, Chavez A, Carrera D, Castillo P. LTP at Hilar Mossy Cell-Dentate Granule Cell Synapses Modulates Dentate Gyrus Output by Increasing Excitation/Inhibition Balance. Neuron. 2017;95:928-943.e3 pubmed publisher
Zhong P, Liu Y, Hu Y, Wang T, Zhao Y, Liu Q. BDNF interacts with endocannabinoids to regulate cocaine-induced synaptic plasticity in mouse midbrain dopamine neurons. J Neurosci. 2015;35:4469-81 pubmed publisher
Parsons M, Kang R, Buren C, Dau A, Southwell A, Doty C, et al. Bidirectional control of postsynaptic density-95 (PSD-95) clustering by Huntingtin. J Biol Chem. 2014;289:3518-28 pubmed publisher
Li C, Dabrowska J, Hazra R, Rainnie D. Synergistic activation of dopamine D1 and TrkB receptors mediate gain control of synaptic plasticity in the basolateral amygdala. PLoS ONE. 2011;6:e26065 pubmed publisher
Hossaini M, Jongen J, Biesheuvel K, Kuhl D, Holstege J. Nociceptive stimulation induces expression of Arc/Arg3.1 in the spinal cord with a preference for neurons containing enkephalin. Mol Pain. 2010;6:43 pubmed publisher
De Chiara V, Angelucci F, Rossi S, Musella A, Cavasinni F, Cantarella C, et al. Brain-derived neurotrophic factor controls cannabinoid CB1 receptor function in the striatum. J Neurosci. 2010;30:8127-37 pubmed publisher

image

image 1 :

Cat.No. 2837 - BDNF (human) CAS No. 218441-99-7

product information

brand :

Tocris

MasterCode :

2837

SKU :

2837/10U

product name :

BDNF (human)

target :

Trk Receptor Activators

category :

Peptides

unit size :

10 ug

purity :

95%

species :

Human

observed molecular weight :

26984

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

BDNF (human) is a member of the neurotrophin growth factor family that binds and activates TrkB and p75 neurotrophin receptors. BDNF enhances the survival, growth and differentiation of neurons. BDNF expression is altered in neurodegenerative disorders such as Parkinson s and Alzheimer s disease. In an animal model of Huntington s disease, BDNF administration or overexpression rescues the disease phenotype.

extended description :

Activates TrkB and p75 receptors

cas num :

218441-99-7

USD :

426 USD

product details :

Activates TrkB and p75 receptors

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage