Bupropion hydrochloride | Tocris Bioscience 2831/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Bupropion hydrochloride

catalog :

2831/50

quantity :

50 mg

price :

196 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Durham E, Howie R, Warren G, LaRue A, Cray J. Direct Effects of Nicotine Exposure on Murine Calvaria and Calvarial Cells. Sci Rep. 2019;9:3805 pubmed publisher
Czysz A, Schappi J, Rasenick M. Lateral diffusion of GÎ±s in the plasma membrane is decreased after chronic but not acute antidepressant treatment: role of lipid raft and non-raft membrane microdomains. Neuropsychopharmacology. 2015;40:766-73 pubmed publisher
Nunes E, Randall P, Hart E, Freeland C, Yohn S, Baqi Y, et al. Effort-related motivational effects of the VMAT-2 inhibitor tetrabenazine: implications for animal models of the motivational symptoms of depression. J Neurosci. 2013;33:19120-30 pubmed publisher
Li Y, Xi D, Roman J, Huang Y, Gao W. Activation of glycogen synthase kinase-3 beta is required for hyperdopamine and D2 receptor-mediated inhibition of synaptic NMDA receptor function in the rat prefrontal cortex. J Neurosci. 2009;29:15551-63 pubmed publisher

product information

brand :

Tocris

catalog number base :

2831

SKU :

2831/50

product name :

Bupropion hydrochloride

units size :

50 mg

description :

Non-selective inhibitor of dopamine and noradrenalin transporters

target :

Dopamine Transporter Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

276.2

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Bupropion hydrochloride is a non-selective inhibitor of dopamine and noradrenalin transporters (Ki values are 1.4, 2.8 and 45 u M for NET, DAT and SERT transporters respectively). Also inhibits neuronal nicotinic acetylcholine receptors. Displays antidepressant activity and augments nicotine self-administration at low doses in vivo .

top caption :

Non-selective inhibitor of dopamine and noradrenalin transporters

extended description :

Non-selective inhibitor of dopamine and noradrenalin transporters

chemical name text :

1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride

formula :

C13H18ClNO.HCl

formula text :

C13H18ClNO.HCl

cas num :

31677-93-7

USD :

196 USD

product details :

Non-selective inhibitor of dopamine and noradrenalin transporters

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage