product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
(+)-Tubocurarine chloride
catalog :
2820/50
quantity :
50 mg
price :
97 USD
more info or order :
citations: 10
Reference
Corns L, Johnson S, Roberts T, Ranatunga K, Hendry A, Ceriani F, et al. Mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation. Nat Commun. 2018;9:4015 pubmed publisher
Roemmich A, Schutte S, O Dowd D. Ex vivo Whole-cell Recordings in Adult Drosophila Brain. Bio Protoc. 2018;8: pubmed publisher
Zhu H, Yan H, Tang N, Li X, Pang P, Li H, et al. Impairments of spatial memory in an Alzheimer's disease model via degeneration of hippocampal cholinergic synapses. Nat Commun. 2017;8:1676 pubmed publisher
TRUSZKOWSKI T, Carrillo O, Bleier J, Ramirez Vizcarrondo C, Felch D, McQuillan M, et al. A cellular mechanism for inverse effectiveness in multisensory integration. elife. 2017;6: pubmed publisher
Zachary S, Fuchs P. Re-Emergent Inhibition of Cochlear Inner Hair Cells in a Mouse Model of Hearing Loss. J Neurosci. 2015;35:9701-6 pubmed publisher
Pinnock F, Bosch D, Brown T, Simons N, Yeomans J, DeOliveira C, et al. Nicotine receptors mediating sensorimotor gating and its enhancement by systemic nicotine. Front Behav Neurosci. 2015;9:30 pubmed publisher
Nagel K, Hong E, Wilson R. Synaptic and circuit mechanisms promoting broadband transmission of olfactory stimulus dynamics. Nat Neurosci. 2015;18:56-65 pubmed publisher
Freeman G, Nakajima M, Ueda H, Herzog E. Picrotoxin dramatically speeds the mammalian circadian clock independent of Cys-loop receptors. J Neurophysiol. 2013;110:103-8 pubmed publisher
Saliba R, Kretschmannova K, Moss S. Activity-dependent phosphorylation of GABAA receptors regulates receptor insertion and tonic current. EMBO J. 2012;31:2937-51 pubmed publisher
Lamy C, Goodchild S, Weatherall K, Jane D, Liégeois J, Seutin V, et al. Allosteric block of KCa2 channels by apamin. J Biol Chem. 2010;285:27067-77 pubmed publisher
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
2820
SKU :
2820/50
product name :
(+)-Tubocurarine chloride
description :
nAChR antagonist
target :
Additional Nicotinic Receptor Antagonists
unit size :
50 mg
category :
Small Molecules
purity :
98%
storage :
Store at +4°C
observed molecular weight :
681.65
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
(+)-Tubocurarine chloride is a competitive, non-selective nicotinic acetylcholine receptor antagonist; causes skeletal muscle relaxation. Also a 5-HT3 and GABAA receptor antagonist.
product keywords :
Nicotinic receptor antagonists Acetylcholine Receptors Non-Selective Subtypes nAChR curare Nicotinic Receptors (Non-selective) 2820,
extended description :
nAChR antagonist
chemical name text :
2,3,13a,14,15,16,25,25a,-Octahydro-9,19-dihydroxy-18,29-dimethoxy-1,14,14-trimethyl-13H-4,6:21,24-dietheno-8,12-metheno-1H-pyrido[3 ,2 :14,15][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolinium chloride hydrochloride
formula :
C37H41ClN2O6.HCl
formula text :
C37H41ClN2O6.HCl
cas num :
57-94-3
USD :
96
USD 2025 :
97 USD
product details :
nAChR antagonist
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK