PI 828 | Tocris Bioscience 2814 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PI 828

catalog :

2814

quantity :

1 mg

price :

106 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Liddell J, Lehtonen S, Duncan C, Keksa Goldsteine V, Levonen A, Goldsteins G, et al. Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes. J Neuroinflammation. 2016;13:49 pubmed publisher
Rogers S, Gahring L. Upregulation of Nicotinic Acetylcholine Receptor alph4+beta2 through a Ligand-Independent PI3Kbeta Mechanism That Is Enhanced by TNFalpha and the Jak2/p38Mapk Pathways. PLoS ONE. 2015;10:e0143319 pubmed publisher
Moser R, Xu C, Kao M, Annis J, Lerma L, Schaupp C, et al. Functional kinomics identifies candidate therapeutic targets in head and neck cancer. Clin Cancer Res. 2014;20:4274-88 pubmed publisher
Grassin Delyle S, Abrial C, Fayad Kobeissi S, Brollo M, Faisy C, Alvarez J, et al. The expression and relaxant effect of bitter taste receptors in human bronchi. Respir Res. 2013;14:134 pubmed publisher
Li J, Kanju P, Patterson M, Chew W, Cho S, Gilmour I, et al. TRPV4-mediated calcium influx into human bronchial epithelia upon exposure to diesel exhaust particles. Environ Health Perspect. 2011;119:784-93 pubmed publisher

product information

brand :

Tocris

master code :

2814

SKU :

2814/1

product name :

PI 828

description :

PI 3-kinase inhibitor, more potent than LY 294002 (Cat. No. 1130)

target :

PI 3-Kinase Inhibitors

category :

Small Molecules

unit size :

1 mg

purity :

99%

observed molecular weight :

322.36

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PI 3-Kinase inhibitor (IC50 values are 0.098, 0.183, 0.227 and 1.967 u M for p110 , p110 , p110 and p110 respectively) that displays higher potency than LY 294002 (Cat No. 1130). Can be immobilized onto a solid phase.

catalog number base :

2814

product keywords :

PI 3-kinase inhibitors inhibits potent LY 294002 PI3K Phosphoinositide 3-Kinases PI828 PI 3-Kinase Inositol Lipids 2814,

extended description :

PI 3-kinase inhibitor, more potent than LY 294002 (Cat. No. 1130)

chemical name text :

2-(4-Morpholinyl)-8-(4-aminopheny)l-4H-1-benzopyran-4-one

formula :

C 19 H 18 N 2 O 3

formula text :

C19H18N2O3

cas num :

942289-87-4

2020 USD :

102

2021 USD :

106 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage