PI 828 | Tocris Bioscience 2814/50 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PI 828

catalog :

2814/50

quantity :

50 mg

price :

905 USD

citations: 3

Reference
Rogers S, Gahring L. Upregulation of Nicotinic Acetylcholine Receptor alph4+beta2 through a Ligand-Independent PI3Kbeta Mechanism That Is Enhanced by TNFalpha and the Jak2/p38Mapk Pathways. PLoS ONE. 2015;10:e0143319 pubmed publisher
Moser R, Xu C, Kao M, Annis J, Lerma L, Schaupp C, et al. Functional kinomics identifies candidate therapeutic targets in head and neck cancer. Clin Cancer Res. 2014;20:4274-88 pubmed publisher
Grassin Delyle S, Abrial C, Fayad Kobeissi S, Brollo M, Faisy C, Alvarez J, et al. The expression and relaxant effect of bitter taste receptors in human bronchi. Respir Res. 2013;14:134 pubmed publisher

product information

CHEMISTRY :

O=C2C=C(N3CCOCC3)OC1=C(C4=CC=C(N)C=C4)C=CC=C12

Stock Reference :

2814/50

Cat Number :

2814

Product Name :

PI 828

Cas Number :

[942289-87-4]

Unit Size :

50 mg

Size :

Unit :

USD :

905 USD

Primary Category :

Enzymes

Secondary Category :

Kinases

Tertiary Category :

PI 3-Kinase

Primary Action :

PI 3-kinase inhibitor, more potent than LY 294002 (Cat. No. 1130)

Biological Description :

PI 3-Kinase inhibitor (IC50 values are 0.098, 0.183, 0.227 and 1.967 muM for p110beta, p110alpha, p110delta and p110gamma respectively) that displays higher potency than LY 294002 (Cat No. 1130). Can be immobilized onto a solid phase.

Storage :

Store at +4°C

Formula :

C19H18N2O3

Molwt :

322.36

Minimum Purity :

> 99%

Solubility :

Soluble to 100 mM in DMSO

RTECS No :

Not available