w-Agatoxin IVA | Tocris Bioscience 2799 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

w-Agatoxin IVA

catalog :

2799

quantity :

10 ug

price :

223 USD

more info or order :

Tocris Bioscience product webpage

citations: 6

Reference
Kim J, Choi S, Lee S, Park K. Voltage-dependent Ca2+ channels promote branching morphogenesis of salivary glands by patterning differential growth. Sci Rep. 2018;8:7566 pubmed publisher
Bellono N, Leitch D, Julius D. Molecular basis of ancestral vertebrate electroreception. Nature. 2017;543:391-396 pubmed publisher
Medrihan L, Cesca F, Raimondi A, Lignani G, Baldelli P, Benfenati F. Synapsin II desynchronizes neurotransmitter release at inhibitory synapses by interacting with presynaptic calcium channels. Nat Commun. 2013;4:1512 pubmed publisher
Higley M, Sabatini B. Competitive regulation of synaptic Ca2+ influx by D2 dopamine and A2A adenosine receptors. Nat Neurosci. 2010;13:958-66 pubmed publisher
Jiang B, Huang S, De Pasquale R, Millman D, Song L, Lee H, et al. The maturation of GABAergic transmission in visual cortex requires endocannabinoid-mediated LTD of inhibitory inputs during a critical period. Neuron. 2010;66:248-59 pubmed publisher
Azad S, Kurz J, Marsicano G, Lutz B, Zieglgänsberger W, Rammes G. Activation of CB1 specifically located on GABAergic interneurons inhibits LTD in the lateral amygdala. Learn Mem. 2008;15:143-52 pubmed publisher

product information

brand :

Tocris

master code :

2799

SKU :

2799/10U

product name :

w-Agatoxin IVA

description :

CaV2.1 blocker

target :

Voltage-gated Calcium Channel Blockers

category :

Peptides

unit size :

10 ug

observed molecular weight :

5202.25

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Selective blocker of P-type calcium channels (IC50 1 - 3 nM). Also inhibits N-type channels at micromolar concentrations.

catalog number base :

2799

product keywords :

Ca2+ channel blockers P-type Calcium CaV Channels voltage-gated voltage-dependent -Agatoxin omega-Agatoxin IVA w-AgatoxinIVA w-Aga-IVA -Aga-IVA venoms w-Aga-IV A Cav2.x Channels 2799, Voltage-gated calcium channel blocker, voltage gated calcium channel, high-voltage activated Ca2+ channel, high voltage gated ca2+ channel

extended description :

CaV2.1 blocker

formula :

C 217 H 360 N 68 O 60 S 10

formula text :

C217H360N68O60S10

cas num :

145017-83-0

2020 USD :

214

2021 USD :

223 USD

alt names :

-Aga-IV A

storage :

Desiccate at -20°C

more info or order :

Tocris Bioscience product webpage