product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
w-Agatoxin IVA
catalog :
2799/10U
quantity :
10 ug
price :
259 USD
more info or order :
citations: 6
Reference
Kim J, Choi S, Lee S, Park K. Voltage-dependent Ca2+ channels promote branching morphogenesis of salivary glands by patterning differential growth. Sci Rep. 2018;8:7566 pubmed publisher
Bellono N, Leitch D, Julius D. Molecular basis of ancestral vertebrate electroreception. Nature. 2017;543:391-396 pubmed publisher
Medrihan L, Cesca F, Raimondi A, Lignani G, Baldelli P, Benfenati F. Synapsin II desynchronizes neurotransmitter release at inhibitory synapses by interacting with presynaptic calcium channels. Nat Commun. 2013;4:1512 pubmed publisher
Higley M, Sabatini B. Competitive regulation of synaptic Ca2+ influx by D2 dopamine and A2A adenosine receptors. Nat Neurosci. 2010;13:958-66 pubmed publisher
Jiang B, Huang S, De Pasquale R, Millman D, Song L, Lee H, et al. The maturation of GABAergic transmission in visual cortex requires endocannabinoid-mediated LTD of inhibitory inputs during a critical period. Neuron. 2010;66:248-59 pubmed publisher
Azad S, Kurz J, Marsicano G, Lutz B, Zieglgänsberger W, Rammes G. Activation of CB1 specifically located on GABAergic interneurons inhibits LTD in the lateral amygdala. Learn Mem. 2008;15:143-52 pubmed publisher
product information
brand :
Tocris
master code :
2799
SKU :
2799/10U
product name :
w-Agatoxin IVA
description :
CaV2.1 blocker
target :
Cav2.x Channel Blockers
category :
Peptides
unit sizes :
10 ug
purity :
95%
observed molecular weight :
5202.25
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
-Agatoxin IVA is a selective blocker of P-type calcium channels (IC50 1 - 3 nM). Also inhibits N-type channels at micromolar concentrations.
extended description :
CaV2.1 blocker
formula :
C 217 H 360 N 68 O 60 S 10
formula text :
C217H360N68O60S10
cas num :
145017-83-0
USD :
259 USD
product details :
CaV2.1 blocker
alt names :
-Aga-IV A
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK