PP 3 | Tocris Bioscience 2794 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PP 3

catalog :

2794

quantity :

10 mg

price :

212 USD

more info or order :

Tocris Bioscience product webpage

citations: 7

Reference
Hass H, Kipkeew F, Gauhar A, Bouché E, May P, Timmer J, et al. Mathematical model of early Reelin-induced Src family kinase-mediated signaling. PLoS ONE. 2017;12:e0186927 pubmed publisher
Li X, Rhee D, Malhotra R, Mayeur C, Hurst L, Ager E, et al. Progesterone receptor membrane component-1 regulates hepcidin biosynthesis. J Clin Invest. 2016;126:389-401 pubmed publisher
Rosas O, Torrado A, Santiago J, Rodríguez A, Salgado I, Miranda J. Long-term treatment with PP2 after spinal cord injury resulted in functional locomotor recovery and increased spared tissue. Neural Regen Res. 2014;9:2164-73 pubmed publisher
Vijayakumar V, Monypenny J, Chen X, Machesky L, Lilla S, Thrasher A, et al. Tyrosine phosphorylation of WIP releases bound WASP and impairs podosome assembly in macrophages. J Cell Sci. 2015;128:251-65 pubmed publisher
Kupferman J, Basu J, Russo M, Guevarra J, Cheung S, Siegelbaum S. Reelin signaling specifies the molecular identity of the pyramidal neuron distal dendritic compartment. Cell. 2014;158:1335-1347 pubmed publisher
Kubota H, Nagao S, Obata K, Hirono M. mGluR1-mediated excitation of cerebellar GABAergic interneurons requires both G protein-dependent and Src-ERK1/2-dependent signaling pathways. PLoS ONE. 2014;9:e106316 pubmed publisher
Chen W, Walwyn W, Ennes H, Kim H, McRoberts J, Marvizon J. BDNF released during neuropathic pain potentiates NMDA receptors in primary afferent terminals. Eur J Neurosci. 2014;39:1439-54 pubmed publisher

product information

brand :

Tocris

master code :

2794

SKU :

2794/10

product name :

PP 3

description :

Negative control for PP 2 (Cat. No. 1407)

target :

Src Family Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

211.22

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Negative control for the Src kinase inhibitor, PP 2. Inhibits EGFR kinase (IC50 = 2.7 u M). . Active Analog also available.

catalog number base :

2794

product keywords :

Negative control PP 2 EGFR-kinases inhibitors inhibits Src negative Epidermal Growth Factors Receptors ErbB Her EGFR Receptor Tyrosine RTKs PP3 Src Kinases EGFR 2794,

extended description :

Negative control for PP 2 (Cat. No. 1407)

chemical name text :

1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

formula :

C 11 H 9 N 5

formula text :

C11H9N5

cas num :

5334-30-5

2020 USD :

205

2021 USD :

212 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage