product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
PP 3
catalog :
2794/10
quantity :
10 mg
price :
267 USD
more info or order :
citations: 8
Reference
Hass H, Kipkeew F, Gauhar A, Bouché E, May P, Timmer J, et al. Mathematical model of early Reelin-induced Src family kinase-mediated signaling. PLoS ONE. 2017;12:e0186927 pubmed publisher
Phan T, Jaruga B, Pingle S, Bandyopadhyay B, Ahern G. Intrinsic Photosensitivity Enhances Motility of T Lymphocytes. Sci Rep. 2016;6:39479 pubmed publisher
Li X, Rhee D, Malhotra R, Mayeur C, Hurst L, Ager E, et al. Progesterone receptor membrane component-1 regulates hepcidin biosynthesis. J Clin Invest. 2016;126:389-401 pubmed publisher
Rosas O, Torrado A, Santiago J, Rodríguez A, Salgado I, Miranda J. Long-term treatment with PP2 after spinal cord injury resulted in functional locomotor recovery and increased spared tissue. Neural Regen Res. 2014;9:2164-73 pubmed publisher
Vijayakumar V, Monypenny J, Chen X, Machesky L, Lilla S, Thrasher A, et al. Tyrosine phosphorylation of WIP releases bound WASP and impairs podosome assembly in macrophages. J Cell Sci. 2015;128:251-65 pubmed publisher
Kupferman J, Basu J, Russo M, Guevarra J, Cheung S, Siegelbaum S. Reelin signaling specifies the molecular identity of the pyramidal neuron distal dendritic compartment. Cell. 2014;158:1335-1347 pubmed publisher
Kubota H, Nagao S, Obata K, Hirono M. mGluR1-mediated excitation of cerebellar GABAergic interneurons requires both G protein-dependent and Src-ERK1/2-dependent signaling pathways. PLoS ONE. 2014;9:e106316 pubmed publisher
Chen W, Walwyn W, Ennes H, Kim H, McRoberts J, Marvizon J. BDNF released during neuropathic pain potentiates NMDA receptors in primary afferent terminals. Eur J Neurosci. 2014;39:1439-54 pubmed publisher
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
2794
SKU :
2794/10
product name :
PP 3
description :
Negative control for PP 2 (Cat. No. 1407)
target :
Src Family Kinase Inhibitors
unit size :
10 mg
category :
Small Molecules
purity :
98%
storage :
Store at -20°C
observed molecular weight :
211.22
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
PP 3 is a negative control for the Src kinase inhibitor, PP 2. Inhibits EGFR kinase (IC50 = 2.7 u M). . Active Analog also available.
product keywords :
Negative control PP 2 EGFR-kinases inhibitors inhibits Src negative Epidermal Growth Factors Receptors ErbB Her EGFR Receptor Tyrosine RTKs PP3 Src Kinases EGFR 2794,
extended description :
Negative control for PP 2 (Cat. No. 1407)
chemical name text :
1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
formula :
C11H9N5
formula text :
C11H9N5
cas num :
5334-30-5
USD :
264
USD 2025 :
267 USD
product details :
Negative control for PP 2 (Cat. No. 1407)
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK