Jasplakinolide | Tocris Bioscience 2792/100 product information

product summary

request information :

company name :

Tocris Bioscience

product type :

chemical

product name :

Jasplakinolide

catalog :

2792/100

quantity :

100µg

price :

295 USD

more info or order :

Tocris Bioscience product webpage

product information

CHEMISTRY :

C[C@H](C[C@H](C)OC1=O)/C=C(C)/C[C@H](C)C(N[C@H](C(N([C@H](CC2=C(Br)NC3=C2C=CC=C3)C(N[C@@H]([C@]4=CC=C(O)C=C4)C1)=O)C)=O)C)=O

Cat Number :

2792/100

Product Name :

Jasplakinolide

Cas Number :

[102396-24-7]

Unit Size :

100µg

Size :

100

Unit :

µg

USD :

295 USD

Primary Category :

Cell Biology

Secondary Category :

Cytoskeleton and Motor Proteins

Tertiary Category :

Actin

Primary Action :

Stabilizes F-actin; promotes actin polymerization

Biological Description :

Rapidly stabilizes pre-formed actin filaments and inhibits their disassembly in vitro. Also induces polymerization of actin monomers into F-actin in vivo. Shown to bind to F-actin competitively with phalloidin (Cat. No. 4535) (Kd ~ 15 nM). Exhibits antifungal and antiproliferative effects (IC50 = 35 nM for antiproliferative activity in PC3 cells). Cell permeable.

Formula :

C36H45BrN4O6

Molwt :

709.67

more info or order :

Tocris Bioscience product webpage