K 579 | Tocris Bioscience 2790/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

K 579

catalog :

2790/10

quantity :

10 mg (also 50 mg)

price :

278 USD

citations: 2

Reference
Fujiwara K, Inoue T, Yorifuji N, Iguchi M, Sakanaka T, Narabayashi K, et al. Combined treatment with dipeptidyl peptidase 4 (DPP4) inhibitor sitagliptin and elemental diets reduced indomethacin-induced intestinal injury in rats via the increase of mucosal glucagon-like peptide-2 concentration. J Clin Biochem Nutr. 2015;56:155-62 pubmed publisher
Inoue T, Higashiyama M, Kaji I, Rudenkyy S, Higuchi K, Guth P, et al. Dipeptidyl peptidase IV inhibition prevents the formation and promotes the healing of indomethacin-induced intestinal ulcers in rats. Dig Dis Sci. 2014;59:1286-95 pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

2790

SKU :

2790/10

product name :

K 579

Description :

Dipeptidyl peptidase IV (DPP-IV) inhibitor

target :

DPPIV/CD26 Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

328.41

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

K 579 is a dipeptidyl peptidase IV inhibitor. Inhibits rat, canine, human and monkey enzymes with IC50 values of 3, 5, 8, and 8 nM respectively. Long-acting hypoglycemic agent; attenuates glucose excursion following glucose loading in Zucker fatty rats.

extended description :

Dipeptidyl peptidase IV (DPP-IV) inhibitor

chemical name text :

(2S)-1-[[[4-Methyl-1-(2-pyrimidinyl)-4-piperidinyl]amino]acetyl]-2-pyrrolidinecarbonitrile

formula :

C 17 H 24 N 6 O

formula text :

C17H24N6O

cas num :

440100-64-1

USD :

278 USD

product details :

Dipeptidyl peptidase IV (DPP-IV) inhibitor

storage :

Desiccate at +4°C