NFPS | Tocris Bioscience 2789/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NFPS

catalog :

2789/10

quantity :

10 mg (also 50 mg)

price :

267 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Romei C, Bonifacino T, Milanese M, Usai C, Raiteri L. Colocalization of neurotransmitter transporters on the plasma membrane of the same nerve terminal may reflect cotransmission. Brain Res Bull. 2016;127:100-110 pubmed publisher
Debrouse L, Hurd B, Kiselycznyk C, Plitt A, Todaro A, Mishina M, et al. Probing the modulation of acute ethanol intoxication by pharmacological manipulation of the NMDAR glycine co-agonist site. Alcohol Clin Exp Res. 2013;37:223-33 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2789

SKU :

2789/10

product name :

NFPS

description :

Selective non-transportable GlyT1 inhibitor

target :

Glycine Transporter Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

393.45

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

NFPS is a selective, non-transportable inhibitor of GlyT1 which displays no activity at GABA or glutamate receptors (IC50 values are 2.8, 9.8 and 56000 nM for hGlyT1, rGlyT1 and rGlyT2 respectively). Enhances the amplitude of the NMDA component of glutamatergic EPSCs. . R-enantiomer also available.

product keywords :

Selective non-transportable GlyT1 inhibitors inhibits Glycine Transporters Monoamine Neurotransmitter (+/-)-NFPS Glycine Transporters 2789,

extended description :

Selective non-transportable GlyT1 inhibitor

chemical name text :

N-[3-([1,1-Biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl]-N-methylglycine

formula :

C24H24FNO3

formula text :

C24H24FNO3

cas num :

405225-21-0

USD :

264

USD 2025 :

267 USD

product details :

Selective non-transportable GlyT1 inhibitor

alt names :

( )-NFPS

more info or order :

Tocris Bioscience product webpage