TCS 46b | Tocris Bioscience 2782 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TCS 46b

catalog :

2782

quantity :

10 mg (also 50 mg)

price :

179 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Carlson S, Kempsell A, Fieber L. Pharmacological evidence that D-aspartate activates a current distinct from ionotropic glutamate receptor currents in Aplysia californica. Brain Behav. 2012;2:391-401 pubmed publisher

product information

brand :

Tocris

master code :

2782

SKU :

2782/10

product name :

TCS 46b

description :

GluN1A/GluN2B-selective NMDA antagonist; orally bioavailable

target :

NMDA Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

345.44

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Orally active, subtype-selective GluN1A/GluN2B (formally NR1A/NR2B) NMDA receptor antagonist (IC50 values are 5.3, 35000 and 100000 nM for GluN1A/2B (NR1A/2B), GluN1A/2B (NR1A/2B) and GluN1A/2C (NR1A/2C) receptor subtypes respectively). Potentiates the effect of L-DOPA in 6-OHDA-lesioned rats following oral administration. . Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions .

catalog number base :

2782

product keywords :

Orally active subtype-selective NR1A/NR2B antagonists Glutamate NMDA Receptors N-Methyl-D-Aspartate iGluR Ionotropic TCS46b GluN1 GluN2B NMDA Receptors 2782,

extended description :

GluN1A/GluN2B-selective NMDA antagonist; orally bioavailable

chemical name text :

1,3-Dihydro-5-[3-[4-(phenylmethyl)-1-2H-benzimidazol-2-one

formula :

C 22 H 23 N 3 O

formula text :

C22H23N3O

cas num :

302799-86-6

2020 USD :

179

2021 USD :

179 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage