product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Probucol
catalog :
2775
quantity :
100 mg
price :
104 USD
more info or order :
citations: 1
Reference
Guo X, Sun X, Hu D, Wang Y, Fujioka H, Vyas R, et al. VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease. Nat Commun. 2016;7:12646 pubmed publisher
product information
brand :
Tocris
master code :
2775
SKU :
2775/100
product name :
Probucol
description :
ABCA1 (CERP) inhibitor; also antioxidant, anti-inflammatory and hypocholesterolemic agent
target :
Additional Antioxidant Compounds
category :
Small Molecules
unit size :
100 mg
purity :
99%
observed molecular weight :
516.84
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
ABCA1 (CERP) inhibitor. Inhibits cholesterol efflux from J774 macrophages expressing ABCA1 by up to 80%. Inhibits atherogenesis in genetically hypercholesterolemic rabbits (Watanabe) and attenuates ischemia/reperfusion-induced cardiomyocyte apoptosis. Antioxidant, anti-inflammatory and hypocholesterolemic agent.
catalog number base :
2775
product keywords :
Antioxidant anti-inflammatory hypocholesterolemic hypocholesterolaemic agent ATP-binding cassette ABCA1 CERP Antioxidants Multidrug Transporters 2775,
extended description :
ABCA1 (CERP) inhibitor; also antioxidant, anti-inflammatory and hypocholesterolemic agent
chemical name text :
4,4 -[(1-Methylethylidene)bis(thio)]bis[2,6-bis(1,1-dimethylethyl)phenol]
formula :
C 31 H 48 O 2 S 2
formula text :
C31H48O2S2
cas num :
23288-49-5
2020 USD :
101
2021 USD :
104 USD
storage :
Desiccate at +4°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK