Probucol | Tocris Bioscience 2775/100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Probucol

catalog :

2775/100

quantity :

100 mg

price :

121 USD

citations: 1

Reference
Guo X, Sun X, Hu D, Wang Y, Fujioka H, Vyas R, et al. VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease. Nat Commun. 2016;7:12646 pubmed publisher

product information

brand :

Tocris

master code :

2775

SKU :

2775/100

product name :

Probucol

description :

ABCA1 (CERP) inhibitor; also antioxidant, anti-inflammatory and hypocholesterolemic agent

target :

Additional Antioxidant Compounds

category :

Small Molecules

unit sizes :

100 mg

purity :

99%

observed molecular weight :

516.84

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Probucol is an ABCA1 (CERP) inhibitor. Inhibits cholesterol efflux from J774 macrophages expressing ABCA1 by up to 80%. Inhibits atherogenesis in genetically hypercholesterolemic rabbits (Watanabe) and attenuates ischemia/reperfusion-induced cardiomyocyte apoptosis. Antioxidant, anti-inflammatory and hypocholesterolemic agent.

extended description :

ABCA1 (CERP) inhibitor; also antioxidant, anti-inflammatory and hypocholesterolemic agent

chemical name text :

4,4 -[(1-Methylethylidene)bis(thio)]bis[2,6-bis(1,1-dimethylethyl)phenol]

formula :

C 31 H 48 O 2 S 2

formula text :

C31H48O2S2

cas num :

23288-49-5

USD :

121 USD

product details :

ABCA1 (CERP) inhibitor; also antioxidant, anti-inflammatory and hypocholesterolemic agent

storage :

Desiccate at +4°C