BX 513 hydrochloride | Tocris Bioscience 2769/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BX 513 hydrochloride

catalog :

2769/10

quantity :

10 mg (also 50 mg)

price :

254 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Lee E, Fertig E, Jin K, Sukumar S, Pandey N, Popel A. Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis. Nat Commun. 2014;5:4715 pubmed publisher
Di Prisco S, Summa M, Chellakudam V, Rossi P, Pittaluga A. RANTES-mediated control of excitatory amino acid release in mouse spinal cord. J Neurochem. 2012;121:428-37 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2769

SKU :

2769/10

product name :

BX 513 hydrochloride

description :

Selective CCR1 antagonist

target :

Chemokine Receptor Antagonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

99%

storage :

Desiccate at +4°C

observed molecular weight :

481.46

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

BX 513 hydrochloride is a selective CCR1 receptor antagonist (Ki values are 0.04, 10, 10 and 10 nM for CCR1, CCR5, CXCR2 and CXCR4 receptors respectively). Inhibits MIP-1 -induced intracellular calcium mobilization (IC50 = 2.5 u M). Also a full inverse agonist at US28, a HCMV-encoded chemokine receptor.

product keywords :

Selective CCR1 antagonists chemokine Receptors BX513 hydrochloride VUF2274 Rantes VUF 2274 Chemokine CC Receptors 2769,

extended description :

Selective CCR1 antagonist

chemical name text :

4-(4-Chlorophenyl)-4-hydroxy- , -diphenyl-1-piperidinepentanenitrile hydrochloride

formula :

C28H29ClN2O.HCl

formula text :

C28H29ClN2O.HCl

cas num :

1216540-18-9

USD :

282

USD 2025 :

254 USD

product details :

Selective CCR1 antagonist

alt names :

VUF 2274

more info or order :

Tocris Bioscience product webpage