L-748,337 | Tocris Bioscience 2760 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

L-748,337

catalog :

2760

quantity :

10 mg (also 50 mg)

price :

197 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

2760

SKU :

2760/10

product name :

L-748,337

description :

Selective 3 antagonist

target :

Adrenergic beta-3 Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

497.61

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Competitive 3-adrenoceptor antagonist that displays selectivity over 1 and 2 receptors (Ki values are 4.0, 204 and 390 nM for 3-, 2- and 1-adrenoceptors respectively). Inhibits cAMP accumulation in response to isoproterenol (IC50 = 6 nM). Reduces iNOS expression, attenuates nitric oxide-induced cell proliferation and induces apoptosis in a melanoma cell line.

catalog number base :

2760

product keywords :

Selective 3-adrenoceptor b3-adrenoceptor antagonists 3-adrenergic b3-adrenergic Receptors Adrenoceptors L748337 Adrenergic Beta-3 Receptors 2760,

extended description :

Selective 3 antagonist

chemical name text :

N-[[3-[(2S)-2-Hydroxy-3-[[2-[4-[(phenylsulfonyl)amino]phenyl]ethyl]amino]propoxy]phenyl]methyl]-acetamide

formula :

C 26 H 31 N 3 O 5 S

formula text :

C26H31N3O5S

cas num :

244192-94-7

2020 USD :

187

2021 USD :

197 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage