product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
L-748,337
catalog :
2760/10
quantity :
10 mg (also 50 mg)
price :
258 USD
more info or order :
Tocris Bioscience product webpage
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
2760
SKU :
2760/10
product name :
L-748,337
description :
Selective 3 antagonist
target :
Adrenergic beta-3 Receptor Antagonists
unit size :
10 mg (also 50 mg)
category :
Small Molecules
purity :
98%
storage :
Store at +4°C
observed molecular weight :
497.61
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
L-748,337 is a competitive 3-adrenoceptor antagonist that displays selectivity over 1 and 2 receptors (Ki values are 4.0, 204 and 390 nM for 3-, 2- and 1-adrenoceptors respectively). Inhibits cAMP accumulation in response to Isoproterenol (IC50 = 6 nM). Reduces iNOS expression, attenuates nitric oxide-induced cell proliferation and induces apoptosis in a melanoma cell line.
product keywords :
Selective 3-adrenoceptor b3-adrenoceptor antagonists 3-adrenergic b3-adrenergic Receptors Adrenoceptors L748337 Adrenergic Beta-3 Receptors 2760,
extended description :
Selective 3 antagonist
chemical name text :
N-[[3-[(2S)-2-Hydroxy-3-[[2-[4-[(phenylsulfonyl)amino]phenyl]ethyl]amino]propoxy]phenyl]methyl]-acetamide
formula :
C26H31N3O5S
formula text :
C26H31N3O5S
cas num :
244192-94-7
USD :
250
USD 2025 :
258 USD
product details :
Selective 3 antagonist
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK