UCB 35625 | Tocris Bioscience 2757 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

UCB 35625

catalog :

2757

quantity :

1 mg (also 10 mg)

price :

147 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Liu J, Chen S, Wang W, Ning B, Chen F, Shen W, et al. Cancer-associated fibroblasts promote hepatocellular carcinoma metastasis through chemokine-activated hedgehog and TGF-? pathways. Cancer Lett. 2016;379:49-59 pubmed publisher

product information

brand :

Tocris

master code :

2757

SKU :

2757/1

product name :

UCB 35625

description :

Potent CCR1 and CCR3 antagonist

target :

Chemokine Receptor Antagonists

category :

Small Molecules

unit size :

1 mg (also 10 mg)

purity :

98%

observed molecular weight :

655.44

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent chemokine CCR1 and CCR3 receptor antagonist. Inhibits MIP-1 -induced chemotaxis in CCR1 transfectants and eotaxin-induced chemotaxis in CCR3 transfectants (IC50 values are 9.57 and 93.8 nM respectively). Antagonizes CCR3-mediated entry of HIV-1 isolate 89.6 into NP-2 cells (IC50 = 57 nM). . Isomer also available.

catalog number base :

2757

product keywords :

Potent CCR1 CCR3 antagonists Chemokine Receptors UCB35625 Rantes Chemokine CC Receptors 2757,

extended description :

Potent CCR1 and CCR3 antagonist

chemical name text :

1,4-trans-1-(1-Cycloocten-1-ylmethyl)-4-[[(2,7-dichloro-9H-xanthen-9-yl)carbonyl]amino]-1-ethylpiperidinium iodide

formula :

C 30 H 37 Cl 2 IN 2 O 2

formula text :

C30H37Cl2IN2O2

cas num :

202796-42-7

2020 USD :

144

2021 USD :

147 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage