UCB 35625 | Tocris Bioscience 2757/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

UCB 35625

catalog :

2757/1

quantity :

1 mg (also 10 mg)

price :

165 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Liu J, Chen S, Wang W, Ning B, Chen F, Shen W, et al. Cancer-associated fibroblasts promote hepatocellular carcinoma metastasis through chemokine-activated hedgehog and TGF-? pathways. Cancer Lett. 2016;379:49-59 pubmed publisher
Gouwy M, De Buck M, PÃ¶rtner N, Opdenakker G, Proost P, Struyf S, et al. Serum amyloid A chemoattracts immature dendritic cells and indirectly provokes monocyte chemotaxis by induction of cooperating CC and CXC chemokines. Eur J Immunol. 2015;45:101-12 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2757

SKU :

2757/1

product name :

UCB 35625

description :

Potent CCR1 and CCR3 antagonist

target :

Chemokine Receptor Antagonists

unit size :

1 mg (also 10 mg)

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

655.44

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

UCB 35625 is a potent chemokine CCR1 and CCR3 receptor antagonist. Inhibits MIP-1 -induced chemotaxis in CCR1 transfectants and eotaxin-induced chemotaxis in CCR3 transfectants (IC50 values are 9.57 and 93.8 nM respectively). Antagonizes CCR3-mediated entry of HIV-1 isolate 89.6 into NP-2 cells (IC50 = 57 nM). . Isomer also available.

product keywords :

Potent CCR1 CCR3 antagonists Chemokine Receptors UCB35625 Rantes Chemokine CC Receptors 2757,

extended description :

Potent CCR1 and CCR3 antagonist

chemical name text :

1,4-trans-1-(1-Cycloocten-1-ylmethyl)-4-[[(2,7-dichloro-9H-xanthen-9-yl)carbonyl]amino]-1-ethylpiperidinium iodide

formula :

C30H37Cl2IN2O2

formula text :

C30H37Cl2IN2O2

cas num :

202796-42-7

USD :

183

USD 2025 :

165 USD

product details :

Potent CCR1 and CCR3 antagonist

more info or order :

Tocris Bioscience product webpage