product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
KF 38789
catalog :
2748
quantity :
10 mg
price :
223 USD
more info or order :
citations: 2
Reference
Li S, Ip C, Tang M, Tang M, Tong Y, Zhang J, et al. Sialyl Lewisx-P-selectin cascade mediates tumor-mesothelial adhesion in ascitic fluid shear flow. Nat Commun. 2019;10:2406 pubmed publisher
Zhao Z, Vajen T, Karshovska E, Dickhout A, Schmitt M, Megens R, et al. Deletion of junctional adhesion molecule A from platelets increases early-stage neointima formation after wire injury in hyperlipidemic mice. J Cell Mol Med. 2017;21:1523-1531 pubmed publisher
product information
brand :
Tocris
master code :
2748
SKU :
2748/10
product name :
KF 38789
description :
Selective inhibitor of P-selectin-mediated cell adhesion
target :
Cell Adhesion Inhibitors
category :
Small Molecules
unit size :
10 mg
purity :
97%
observed molecular weight :
375.44
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Selective inhibitor of P-selectin-mediated cell adhesion (IC50 = 1.97 u M) that displays no effects on L-selectin- and E-selectin-mediated adhesion. Blocks P-selectin-mediated binding in vitro and leukocyte accumulation in vivo .
catalog number base :
2748
product keywords :
Selective inhibitors inhibits P-selectin-mediated cell adhesio Adhesion Molecules KF38789 Cell Adhesion Molecules 2748,
extended description :
Selective inhibitor of P-selectin-mediated cell adhesion
chemical name text :
3-[7-(2,4-Dimethoxyphenyl)-2,3,6,7-tetrahydro-1,4-thiazepin-5-yl]-4-hydroxy-6-methyl-2H-pyran-2-one
formula :
C 19 H 21 NO 5 S
formula text :
C19H21NO5S
cas num :
257292-29-8
2020 USD :
214
2021 USD :
223 USD
storage :
Desiccate at +4°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK