KF 38789 | Tocris Bioscience 2748/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

KF 38789

catalog :

2748/10

quantity :

10 mg

price :

287 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Neufeld L, Yeini E, Reisman N, Shtilerman Y, Ben Shushan D, Pozzi S, et al. Microengineered perfusable 3D-bioprinted glioblastoma model for in vivo mimicry of tumor microenvironment. Sci Adv. 2021;7: pubmed publisher
Li S, Ip C, Tang M, Tang M, Tong Y, Zhang J, et al. Sialyl Lewisx-P-selectin cascade mediates tumor-mesothelial adhesion in ascitic fluid shear flow. Nat Commun. 2019;10:2406 pubmed publisher
Zhao Z, Vajen T, Karshovska E, Dickhout A, Schmitt M, Megens R, et al. Deletion of junctional adhesion molecule A from platelets increases early-stage neointima formation after wire injury in hyperlipidemic mice. J Cell Mol Med. 2017;21:1523-1531 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2748

SKU :

2748/10

product name :

KF 38789

description :

Selective inhibitor of P-selectin-mediated cell adhesion

target :

Cell Adhesion Inhibitors

unit size :

10 mg

category :

Small Molecules

purity :

97%

storage :

Desiccate at +4°C

observed molecular weight :

375.44

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

KF 38789 is a selective inhibitor of P-selectin-mediated cell adhesion (IC50 = 1.97 u M) that displays no effects on L-selectin- and E-selectin-mediated adhesion. KF 38789 blocks P-selectin-mediated binding in vitro and leukocyte accumulation in vivo .

product keywords :

Selective inhibitors inhibits P-selectin-mediated cell adhesio Adhesion Molecules KF38789 Cell Adhesion Molecules 2748,

extended description :

Selective inhibitor of P-selectin-mediated cell adhesion

chemical name text :

3-[7-(2,4-Dimethoxyphenyl)-2,3,6,7-tetrahydro-1,4-thiazepin-5-yl]-4-hydroxy-6-methyl-2H-pyran-2-one

formula :

C19H21NO5S

formula text :

C19H21NO5S

cas num :

257292-29-8

USD :

278

USD 2025 :

287 USD

product details :

Selective inhibitor of P-selectin-mediated cell adhesion

more info or order :

Tocris Bioscience product webpage