NNC 05-2090 hydrochloride | Tocris Bioscience 2747 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NNC 05-2090 hydrochloride

catalog :

2747

quantity :

10 mg (also 50 mg)

price :

222 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Wang P, Eshaq R, Meshul C, Moore C, Hood R, Leidenheimer N. Neuronal gamma-aminobutyric acid (GABA) type A receptors undergo cognate ligand chaperoning in the endoplasmic reticulum by endogenous GABA. Front Cell Neurosci. 2015;9:188 pubmed publisher

product information

brand :

Tocris

master code :

2747

SKU :

2747/10

product name :

NNC 05-2090 hydrochloride

description :

GABA uptake inhibitor; moderately BGT-1 selective

target :

GABA Transporter Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

451.01

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

GABA uptake inhibitor that displays moderate selectivity for BGT-1 (mGAT-2) transporters (Ki values are 1.4, 15, 19 and 41 u M for hBGT-1, hGAT-3, hGAT-1 and hGAT-2 respectively). Anticonvulsive; inhibits sound-induced tonic and clonic convulsions in DBA/2 mice. Also displays affinity at 1- and D2-receptors (IC50 values are 266 and 1632 nM respectively).

catalog number base :

2747

product keywords :

GABA reuptake inhibitors inhibits moderately BGT-1 selective Transporters Monoamine Neurotransmitter NNC052090 hydrochloride GABA Transporters 2747,

extended description :

GABA uptake inhibitor; moderately BGT-1 selective

chemical name text :

1-[3-(9H-Carbazol-9-yl)propyl]-4-(2-methoxyphenyl)-4-piperidinol hydrochloride

formula :

C 27 H 30 N 2 O 2 .HCl

formula text :

C27H30N2O2.HCl

cas num :

184845-18-9

2020 USD :

222

2021 USD :

222 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage