Caffeic acid phenethyl ester | Tocris Bioscience 2743 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Caffeic acid phenethyl ester

catalog :

2743

quantity :

10 mg (also 50 mg)

price :

51 USD

more info or order :

Tocris Bioscience product webpage

citations: 11

Reference
Messerschmidt L, Fischer S, Wiedemann P, Bringmann A, Hollborn M. Osmotic induction of cyclooxygenase-2 in RPE cells: Stimulation of inflammasome activation. Mol Vis. 2019;25:329-344 pubmed
Tawara K, Scott H, Emathinger J, Wolf C, LaJoie D, Hedeen D, et al. HIGH expression of OSM and IL-6 are associated with decreased breast cancer survival: synergistic induction of IL-6 secretion by OSM and IL-1β. Oncotarget. 2019;10:2068-2085 pubmed publisher
Kleiner J, Hollborn M, Wiedemann P, Bringmann A. Activator protein-1 contributes to the NaCl-induced expression of VEGF and PlGF in RPE cells. Mol Vis. 2018;24:647-666 pubmed
Ciarlo C, Kaufman C, Kinikoglu B, Michael J, Yang S, D Amato C, et al. A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development. elife. 2017;6: pubmed publisher
Mia M, Bank R. The pro-fibrotic properties of transforming growth factor on human fibroblasts are counteracted by caffeic acid by inhibiting myofibroblast formation and collagen synthesis. Cell Tissue Res. 2016;363:775-89 pubmed publisher
Brosig A, Kuhrt H, Wiedemann P, Kohen L, Bringmann A, Hollborn M. Gene expression regulation in retinal pigment epithelial cells induced by viral RNA and viral/bacterial DNA. Mol Vis. 2015;21:1000-16 pubmed
Ankathatti Munegowda M, Hu J. Transient blocking of NK cell function with small molecule inhibitors for helper dependant adenoviral vector-mediated gene delivery. Cell Biosci. 2015;5:29 pubmed publisher
Ong C, Elkington P, Brilha S, Ugarte Gil C, Tome Esteban M, Tezera L, et al. Neutrophil-Derived MMP-8 Drives AMPK-Dependent Matrix Destruction in Human Pulmonary Tuberculosis. PLoS Pathog. 2015;11:e1004917 pubmed publisher
Hollborn M, Vogler S, Reichenbach A, Wiedemann P, Bringmann A, Kohen L. Regulation of the hyperosmotic induction of aquaporin 5 and VEGF in retinal pigment epithelial cells: involvement of NFAT5. Mol Vis. 2015;21:360-77 pubmed
Pysz M, Hao F, Hizli A, Lum M, Swetzig W, Black A, et al. Differential regulation of cyclin D1 expression by protein kinase C ? and ? signaling in intestinal epithelial cells. J Biol Chem. 2014;289:22268-83 pubmed publisher
Zhu J, Sun L, Lin S, Zhao R, Zhou L, Fang D, et al. BlyS is up-regulated by hypoxia and promotes migration of human breast cancer cells. J Exp Clin Cancer Res. 2012;31:31 pubmed publisher

product information

brand :

Tocris

master code :

2743

SKU :

2743/10

product name :

Caffeic acid phenethyl ester

description :

Specific inhibitor of NF- B activation

target :

NFkB / IkB Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

284.31

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Antioxidant, antimitogenic, anticarcinogenic, anti-inflammatory and antiviral. Specifically inhibits NF- B activation and inhibits the growth of transformed cells. Also suppresses lipid peroxidation and inhibits ornithine decarboxylase, protein tyrosine kinase and lipoxygenase activities.

catalog number base :

2743

extended description :

Specific inhibitor of NF- B activation

chemical name text :

3-(3,4-Dihydroxyphenyl)-2-propenoic acid 2-phenylethyl ester

formula :

C 17 H 16 O 4

formula text :

C17H16O4

cas num :

104594-70-9

USD :

51 USD

alt names :

CAPE

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage