SB 258719 hydrochloride | Tocris Bioscience 2726/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SB 258719 hydrochloride

catalog :

2726/10

quantity :

10 mg (also 50 mg)

price :

241 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Dominguez Soto A, Usategui A, Casas Engel M, Simón Fuentes M, Nieto C, Cuevas V, et al. Serotonin drives the acquisition of a profibrotic and anti-inflammatory gene profile through the 5-HT7R-PKA signaling axis. Sci Rep. 2017;7:14761 pubmed publisher
Zhao X, Wang C, Cui W, Ma Q, Zhou W. Fisetin exerts antihyperalgesic effect in a mouse model of neuropathic pain: engagement of spinal serotonergic system. Sci Rep. 2015;5:9043 pubmed publisher
Johnson O, Becnel J, Nichols C. Serotonin receptor activity is necessary for olfactory learning and memory in Drosophila melanogaster. Neuroscience. 2011;192:372-81 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2726

SKU :

2726/10

product name :

SB 258719 hydrochloride

description :

Selective 5-HT7 antagonist

target :

5-HT7 Receptor Antagonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

99%

storage :

Desiccate at RT

observed molecular weight :

374.97

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SB 258719 hydrochloride is a selective 5-HT7 receptor antagonist that displays 100-fold selectivity over a range of other receptors. Reverses the hypothermic effect of 5-CT in mice following i.p. administration.

product keywords :

Selective 5-HT7 antagonists Serotonin Receptors 5-Hydroxytryptamine SB258719 hydrochloride GlaxoSmithKline GSK 5-HT7 Receptors 2726,

extended description :

Selective 5-HT7 antagonist

chemical name text :

3-Methyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]-N-methylbenzenesulfonamide hydrochloride

formula :

C18H30N2O2S.HCl

formula text :

C18H30N2O2S.HCl

cas num :

1217674-10-6

USD :

238

USD 2025 :

241 USD

product details :

Selective 5-HT7 antagonist

more info or order :

Tocris Bioscience product webpage