product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
SB 265610
catalog :
2724/1
quantity :
1 mg (also 10 mg, 50 mg)
price :
131 USD
more info or order :
citations: 11
Reference |
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Lavoie Lamoureux A, Moran K, Beauchamp G, Mauel S, Steinbach F, Lefebvre Lavoie J, et al. IL-4 activates equine neutrophils and induces a mixed inflammatory cytokine expression profile with enhanced neutrophil chemotactic mediator release ex vivo. Am J Physiol Lung Cell Mol Physiol. 2010;299:L472-82 pubmed publisher
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product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
2724
SKU :
2724/1
product name :
SB 265610
description :
Potent CXCR2 antagonist
target :
Chemokine Receptor Antagonists
unit size :
1 mg (also 10 mg, 50 mg)
category :
Small Molecules
purity :
98%
storage :
Store at RT
observed molecular weight :
357.16
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
SB 265610 is a potent CXCR2 antagonist that inhibits CINC-1-mediated but not C5a-mediated Ca2+ mobilization (IC50 values are 3.4 and 6800 nM respectively). Inhibits CINC-induced chemotaxis and attenuates neutrophil accumulation in inflammatory lung injury in vivo .
product keywords :
Potent CXCR2 antagonists Chemokine Receptors SB265610 GlaxoSmithKline GSK Chemokine CXC Receptors 2724,
extended description :
Potent CXCR2 antagonist
chemical name text :
N-(2-Bromophenyl)-N -(7-cyano-1H-benzotriazol-4-yl)urea
formula :
C14H9BrN6O
formula text :
C14H9BrN6O
cas num :
211096-49-0
USD :
129
USD 2025 :
131 USD
product details :
Potent CXCR2 antagonist
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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