product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
PSB 0474
catalog :
2715
quantity :
1 mg
price :
338 USD
more info or order :
citations: 5
Reference
Quintas C, Pinho D, Pereira C, Saraiva L, Gonçalves J, Queiroz G. Microglia P2Y₆ receptors mediate nitric oxide release and astrocyte apoptosis. J Neuroinflammation. 2014;11:141 pubmed publisher
Barragán Iglesias P, Pineda Farias J, Cervantes Durán C, Bravo Hernández M, Rocha González H, Murbartián J, et al. Role of spinal P2Y6 and P2Y11 receptors in neuropathic pain in rats: possible involvement of glial cells. Mol Pain. 2014;10:29 pubmed publisher
Carneiro I, Timóteo M, Silva I, Vieira C, Baldaia C, Ferreirinha F, et al. Activation of P2Y6 receptors increases the voiding frequency in anaesthetized rats by releasing ATP from the bladder urothelium. Br J Pharmacol. 2014;171:3404-19 pubmed publisher
Gao Z, Wei Q, Jayasekara M, Jacobson K. The role of P2Y(14) and other P2Y receptors in degranulation of human LAD2 mast cells. Purinergic Signal. 2013;9:31-40 pubmed publisher
Kataoka A, Koga Y, Uesugi A, Tozaki Saitoh H, Tsuda M, Inoue K. Involvement of vasodilator-stimulated phosphoprotein in UDP-induced microglial actin aggregation via PKC- and Rho-dependent pathways. Purinergic Signal. 2011;7:403-11 pubmed publisher
product information
brand :
Tocris
master code :
2715
SKU :
2715/1
product name :
PSB 0474
description :
Potent and selective P2Y6 agonist
target :
P2Y Receptor Agonists
category :
Small Molecules
unit size :
1 mg
purity :
98%
observed molecular weight :
566.26
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Potent and selective P2Y6 receptor agonist (EC50 values are 70, 1000 and 10000 nM for P2Y6, P2Y2 and P2Y4 receptors respectively). Induces contractions of rat isolated intrapulmonary arteries in vitro .
catalog number base :
2715
extended description :
Potent and selective P2Y6 agonist
chemical name text :
3-(2-Oxo-2-phenylethyl)-uridine-5 -diphosphate disodium salt
formula :
C 17 H 18 N 2 Na 2 O 13 P 2
formula text :
C17H18N2Na2O13P2
USD :
338 USD
alt names :
3-Phenacyl UDP disodium salt
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK