BAY 55-9837 | Tocris Bioscience 2711 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BAY 55-9837

catalog :

2711

quantity :

1 mg

price :

374 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Hamnett R, Crosby P, Chesham J, Hastings M. Vasoactive intestinal peptide controls the suprachiasmatic circadian clock network via ERK1/2 and DUSP4 signalling. Nat Commun. 2019;10:542 pubmed publisher
Pecoraro V, Sardone L, Chisari M, Licata F, Li Volsi G, Perciavalle V, et al. A subnanomolar concentration of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) pre-synaptically modulates glutamatergic transmission in the rat hippocampus acting through acetylcholine. Neuroscience. 2017;340:551-562 pubmed publisher
Toda A, Huganir R. Regulation of AMPA receptor phosphorylation by the neuropeptide PACAP38. Proc Natl Acad Sci U S A. 2015;112:6712-7 pubmed publisher
Pantazopoulos H, Dolatshad H, Davis F. Chronic stimulation of the hypothalamic vasoactive intestinal peptide receptor lengthens circadian period in mice and hamsters. Am J Physiol Regul Integr Comp Physiol. 2010;299:R379-85 pubmed publisher

product information

brand :

Tocris

master code :

2711

SKU :

2711/1

product name :

BAY 55-9837

description :

Potent and selective VPAC2 agonist

target :

VIP Receptor Agonists

category :

Peptides

unit size :

1 mg

observed molecular weight :

3742.29

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Selective VPAC2 receptor agonist (EC50 values are 0.4, 100 and 1000 nM for VPAC2, VPAC1 and PAC1, respectively in a cAMP accumulation assay; IC50 values are 60, 8700 and 10000 nM for VPAC2, VPAC1 and PAC1, respectively in a competition binding assay). Stimulates glucose-dependent insulin secretion in isolated human pancreatic islets. Reduces HIV-1 viral replication and shows cooperative effects when given in conjunction with VPAC1 agonists.

catalog number base :

2711

extended description :

Potent and selective VPAC2 agonist

formula :

C 167 H 270 N 52 O 46

formula text :

C167H270N52O46

cas num :

463930-25-8

USD :

374 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage